Data on caplacizumab use for thrombotic thrombocytopenic purpura (TTP) in Italy are missing.•Twenty-six Italian patients were treated with caplacizumab for an acute immune TTP episode.•Caplacizumab was effective in treating acute TTP in the Italian real-world clinical setting.•Two major bleeds leading to drug discontinuation were observed.
Caplacizumab use for immune thrombotic thrombocytopenic purpura: the Milan thrombotic thrombocytopenic purpura registry / P. Agosti, P. De Leo, M. Capecchi, B. Ferrari, I. Mancini, S. Gattillo, S.M. Trisolini, E. Rinaldi, G.M. Podda, L. Prezioso, P. Salutari, L. Facchini, D. Caramazza, G. Tolomelli, A. Artoni, F. Peyvandi. - In: RESEARCH AND PRACTICE IN THROMBOSIS AND HAEMOSTASIS. - ISSN 2475-0379. - 7:6(2023 Aug), pp. 102185.1-102185.5. [10.1016/j.rpth.2023.102185]
Caplacizumab use for immune thrombotic thrombocytopenic purpura: the Milan thrombotic thrombocytopenic purpura registry
P. AgostiPrimo
;M. Capecchi;S. Gattillo;G.M. Podda;A. Artoni;F. PeyvandiUltimo
2023
Abstract
Data on caplacizumab use for thrombotic thrombocytopenic purpura (TTP) in Italy are missing.•Twenty-six Italian patients were treated with caplacizumab for an acute immune TTP episode.•Caplacizumab was effective in treating acute TTP in the Italian real-world clinical setting.•Two major bleeds leading to drug discontinuation were observed.
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