: A facile and convenient lipase-catalyzed flow approach for the chemoselective synthesis of tyrosol and hydroxytyrosol methyl carbonates has been developed in neat dimethylcarbonate. The products were obtained in quantitative yield with high catalyst productivity. The biocatalytic approach was then exploited for the preparation of value-added symmetrical tyrosol and hydroxytyrosol carbonates.

A facile and convenient lipase-catalyzed flow approach for the chemoselective synthesis of tyrosol and hydroxytyrosol methyl carbonates has been developed in neat dimethylcarbonate. The products were obtained in quantitative yield with high catalyst productivity. The biocatalytic approach was then exploited for the preparation of value-added symmetrical tyrosol and hydroxytyrosol carbonates.

Lipase-mediated flow synthesis of nature-inspired phenolic carbonates / S. Vicinanza, F. Annunziata, D. Pecora, A. Pinto, L. Tamborini. - In: RSC ADVANCES. - ISSN 2046-2069. - 13:33(2023), pp. 22901-22904. [10.1039/d3ra04735k]

Lipase-mediated flow synthesis of nature-inspired phenolic carbonates

S. Vicinanza
Primo
;
F. Annunziata
Secondo
;
D. Pecora;A. Pinto
Penultimo
;
L. Tamborini
Ultimo
2023

Abstract

A facile and convenient lipase-catalyzed flow approach for the chemoselective synthesis of tyrosol and hydroxytyrosol methyl carbonates has been developed in neat dimethylcarbonate. The products were obtained in quantitative yield with high catalyst productivity. The biocatalytic approach was then exploited for the preparation of value-added symmetrical tyrosol and hydroxytyrosol carbonates.
: A facile and convenient lipase-catalyzed flow approach for the chemoselective synthesis of tyrosol and hydroxytyrosol methyl carbonates has been developed in neat dimethylcarbonate. The products were obtained in quantitative yield with high catalyst productivity. The biocatalytic approach was then exploited for the preparation of value-added symmetrical tyrosol and hydroxytyrosol carbonates.
Settore CHIM/08 - Chimica Farmaceutica
Settore CHIM/10 - Chimica degli Alimenti
   MUSA - Multilayered Urban Sustainability Actiona
   MUSA
   MINISTERO DELL'UNIVERSITA' E DELLA RICERCA
2023
28-lug-2023
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2434/1001030
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