Nome |
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Cooperation between MYC and β-catenin in liver tumorigenesis requires Yap/Taz, file dfa8b9a2-3d48-748b-e053-3a05fe0a3a96
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598
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VE-Cadherin-Mediated Epigenetic Regulation of Endothelial Gene Expression, file dfa8b99a-76ba-748b-e053-3a05fe0a3a96
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273
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Quantitative mass spectrometry of histones H3.2 and H3.3 in Suz12-deficient mouse embryonic stem cells reveals distinct, dynamic post-translational modifications at Lys-27 and Lys-36, file dfa8b99b-bf8c-748b-e053-3a05fe0a3a96
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230
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Focal adhesion kinase depletion reduces human hepatocellular carcinoma growth by repressing enhancer of zeste homolog 2, file dfa8b99a-dc4b-748b-e053-3a05fe0a3a96
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215
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Dissecting the role of H3K27 acetylation and methylation in PRC2 mediated control of cellular identity, file dfa8b99e-f15f-748b-e053-3a05fe0a3a96
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198
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Functional Landscape of PCGF Proteins Reveals Both RING1A/B-Dependent-and RING1A/B-Independent-Specific Activities, file dfa8b99f-a3f4-748b-e053-3a05fe0a3a96
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193
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EZH2 is downstream of the pRB-E2F pathway, essential for proliferation and amplified in cancer, file dfa8b99b-db13-748b-e053-3a05fe0a3a96
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171
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Characterization of an antagonistic switch between histone H3 lysine 27 methylation and acetylation in the transcriptional regulation of Polycomb group target genes, file dfa8b99b-4d2a-748b-e053-3a05fe0a3a96
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158
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Genome-wide mapping of polycomb target genes unravels their roles in cell fate transitions, file dfa8b99b-fd1e-748b-e053-3a05fe0a3a96
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157
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The H3K36me2 Methyltransferase Nsd1 Demarcates PRC2-Mediated H3K27me2 and H3K27me3 Domains in Embryonic Stem Cells, file dfa8b9a0-1e64-748b-e053-3a05fe0a3a96
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152
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The polycomb group protein Suz12 is required for embryonic stem cell differentiation, file dfa8b99b-c440-748b-e053-3a05fe0a3a96
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147
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Polycomb complexes act redundantly to repress genomic repeats and genes, file dfa8b99b-c7b4-748b-e053-3a05fe0a3a96
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147
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Polycomb proteins control proliferation and transformation independently of cell cycle checkpoints by regulating DNA replication, file dfa8b992-79c8-748b-e053-3a05fe0a3a96
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146
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Loss of PRC1 activity in different stem cell compartments activates a common transcriptional program with cell type–dependent outcomes, file dfa8b99f-9717-748b-e053-3a05fe0a3a96
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137
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BAP1 activity regulates PcG occupancy and global chromatin condensation counteracting diffuse PCGF3/5-dependent H2AK119ub1 deposition, file dfa8b9a5-5489-748b-e053-3a05fe0a3a96
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132
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Expression-profiling of apoptosis induced by ablation of the long ncRNA TRPM2-AS in prostate cancer cell, file dfa8b99a-fbf4-748b-e053-3a05fe0a3a96
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127
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Suz12 is essential for mouse development and for EZH2 histone methyltransferase activity, file dfa8b99b-bd88-748b-e053-3a05fe0a3a96
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127
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Polycomb complex 2 is required for E-cadherin repression by the snail1 transcription factor, file dfa8b99c-0993-748b-e053-3a05fe0a3a96
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126
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Isolation of chromatin from dysfunctional telomeres reveals an important role for Ring1b in NHEJ-mediated chromosome fusions, file dfa8b99a-ef12-748b-e053-3a05fe0a3a96
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125
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Regulation of stem cell differentiation by histone methyltransferases and demethylases, file dfa8b99f-63a7-748b-e053-3a05fe0a3a96
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125
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Chromatin regulated interchange between polycomb repressive complex 2 (PRC2)-Ezh2 and PRC2-Ezh1 complexes controls myogenin activation in skeletal muscle cells, file dfa8b99a-ed59-748b-e053-3a05fe0a3a96
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124
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Yin Yang 1 extends the Myc-related transcription factors network in embryonic stem cells, file dfa8b99a-f67e-748b-e053-3a05fe0a3a96
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118
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Coordinated regulation of transcriptional repression by the RBP2 H3K4 demethylase and Polycomb-Repressive Complex 2, file dfa8b99b-e69a-748b-e053-3a05fe0a3a96
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116
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EpiMINE, a computational program for mining epigenomic data, file dfa8b99b-fbd3-748b-e053-3a05fe0a3a96
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113
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Maintenance of leukemic cell identity by the activity of the Polycomb complex PRC1 in mice, file dfa8b996-f259-748b-e053-3a05fe0a3a96
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111
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The polycomb repressive complex 2 is a potential target of SUMO modifications, file dfa8b99b-94e8-748b-e053-3a05fe0a3a96
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110
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Histone H2AK119 Mono-Ubiquitination Is Essential for Polycomb-Mediated Transcriptional Repression, file dfa8b9a3-8c06-748b-e053-3a05fe0a3a96
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109
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Deregulated E2F activity induces hyperplasia and senescence-like features in the mouse pituitary gland, file dfa8b99b-4d2b-748b-e053-3a05fe0a3a96
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104
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NPAT expression is regulated by E2F and is essential for cell cycle progression, file dfa8b99b-cd79-748b-e053-3a05fe0a3a96
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103
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Antagonism between DNA and H3K27 methylation at the imprinted Rasgrf1 locus, file dfa8b99b-8951-748b-e053-3a05fe0a3a96
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99
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Intestinal differentiation involves cleavage of histone H3 N-terminal tails by multiple proteases, file dfa8b9a5-cbd1-748b-e053-3a05fe0a3a96
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75
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Transcription factor TLX1 controls retinoic acid signaling to ensure spleen development, file dfa8b9a3-722b-748b-e053-3a05fe0a3a96
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64
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Polycomb group ring finger protein 6 suppresses Myc-induced lymphomagenesis, file fd39ab38-f246-4762-aa95-403203b288d8
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14
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Polycomb Complex PRC1 Preserves Intestinal Stem Cell Identity by Sustaining Wnt/β-Catenin Transcriptional Activity, file dfa8b99a-c198-748b-e053-3a05fe0a3a96
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8
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Fam60a defines a variant Sin3a-Hdac complex in embryonic stem cells required for self-renewal, file dfa8b99a-e909-748b-e053-3a05fe0a3a96
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8
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JARID2 regulates binding of the Polycomb repressive complex 2 to target genes in ES cells, file dfa8b99b-c7c1-748b-e053-3a05fe0a3a96
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7
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Histone H2AK119 Mono-Ubiquitination Is Essential for Polycomb-Mediated Transcriptional Repression, file b4ddc53b-8352-46a1-87ea-35a9d68f6b39
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6
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Polycomb-Dependent H3K27me1 and H3K27me2 Regulate Active Transcription and Enhancer Fidelity, file dfa8b99b-1ae3-748b-e053-3a05fe0a3a96
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6
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Amplification of Mdmx (or Mdm4) directly contributes to tumor formation by inhibiting p53 tumor suppressor activity, file dfa8b99b-592f-748b-e053-3a05fe0a3a96
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5
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Antisense transcription at the TRPM2 locus as a novel prognostic marker and therapeutic target in prostate cancer, file dfa8b999-b8a2-748b-e053-3a05fe0a3a96
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4
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Antisense transcription at the TRPM2 locus as a novel prognostic marker and therapeutic target in prostate cancer, file dfa8b999-d14f-748b-e053-3a05fe0a3a96
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4
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Precision mapping of coexisting modifications in histone H3 tails from embryonic stem cells by ETD-MS/MS, file dfa8b99a-c3d4-748b-e053-3a05fe0a3a96
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4
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Epigenetic methylations and their connections with metabolism, file dfa8b99b-2757-748b-e053-3a05fe0a3a96
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4
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BAP1 enhances Polycomb repression by counteracting widespread H2AK119ub1 deposition and chromatin condensation, file 8bc9f6a9-7530-41a2-8e9f-a697c669bc41
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3
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The Dual Role of EPOP and Elongin BC in Controlling Transcriptional Activity, file dfa8b99a-c292-748b-e053-3a05fe0a3a96
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3
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Emerging roles for Polycomb proteins in cancer, file dfa8b99a-cd46-748b-e053-3a05fe0a3a96
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3
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The controversial role of the Polycomb group proteins in transcription and cancer : how much do we not understand Polycomb proteins?, file dfa8b99a-ece9-748b-e053-3a05fe0a3a96
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3
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Control of adult intestinal identity by the Polycomb repressive machinery, file dfa8b99b-0742-748b-e053-3a05fe0a3a96
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3
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Tet Proteins Connect the O-Linked N-acetylglucosamine Transferase Ogt to Chromatin in Embryonic Stem Cells, file dfa8b99b-1c45-748b-e053-3a05fe0a3a96
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3
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Increased Lactate Secretion by Cancer Cells Sustains Non-cell-autonomous Adaptive Resistance to MET and EGFR Targeted Therapies, file dfa8b99c-fef7-748b-e053-3a05fe0a3a96
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3
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PRC2 preserves intestinal progenitors and restricts secretory lineage commitment, file dfa8b99a-c444-748b-e053-3a05fe0a3a96
|
2
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Increased Lactate Secretion by Cancer Cells Sustains Non-cell-autonomous Adaptive Resistance to MET and EGFR Targeted Therapies, file dfa8b99c-3dc4-748b-e053-3a05fe0a3a96
|
1
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Dysfunctional polycomb transcriptional repression contributes to lamin A/C-dependent muscular dystrophy, file dfa8b9a9-7903-748b-e053-3a05fe0a3a96
|
1
|
Totale |
5025 |