CRISTOFANI, RICCARDO MARIA
CRISTOFANI, RICCARDO MARIA
Dipartimento di Scienze Farmacologiche e Biomolecolari
Identification of HSPB8 modulators counteracting misfolded protein accumulation in neurodegenerative diseases
2023 M. Chierichetti, M. Cerretani, A. Ciammaichella, V. Crippa, P. Rusmini, V. Ferrari, B. Tedesco, E. Casarotto, M. Cozzi, F. Mina, P. Pramaggiore, M. Galbiati, M. Piccolella, A. Bresciani, R. Cristofani, A. Poletti
Frameshift mutations in the heat shock protein B8 cause its aggregation and impair proteostasis in neuromyopathies
2023 B. Tedesco, L. Vendredy, E. Adriaenssens, M. Cozzi, B. Asselbergh, V. Crippa, R. Cristofani, P. Rusmini, V. Ferrari, E. Casarotto, M. Chierichetti, P. Pramaggiore, M. Galbiati, M. Piccolella, T. Laurenzi, I. Eberini, L. Weiss, V. Kimonis, V. Timmerman, A. Poletti
Molecular mechanisms in KIF5A-related neurodegeneration
2023 M. Cozzi, B. Tedesco, V. Ferrari, E. Casarotto, M. Chierichetti, P. Pramaggiore, M. Piccolella, M. Galbiati, P. Rusmini, V. Crippa, C. Gellera, S. Magri, S. Santangelo, A. Ratti, R. Cristofani, F. Taroni, A. Poletti
STUB1 mutants effect on TBP behavior in digenic spinocerebellar ataxia type 17
2023 P. Pramaggiore, M. Stefania, M. Chierichetti, P. Rusmini, V. Ferrari, B. Tedesco, M. Cozzi, E. Casarotto, M. Piccolella, V. Crippa, M. Galbiati, B. Daniela Di, T. Franco, A. Poletti, R.M. Cristofani
HSPB8 frameshift mutant aggregates weaken chaperone-assisted selective autophagy in neuromyopathies
2023 B. Tedesco, L. Vendredy, E. Adriaenssens, M. Cozzi, B. Asselbergh, V. Crippa, R. Cristofani, P. Rusmini, V. Ferrari, E. Casarotto, M. Chierichetti, F. Mina, P. Pramaggiore, M. Galbiati, M. Piccolella, J. Baets, F. Baeke, R. De Rycke, V. Mouly, T. Laurenzi, I. Eberini, A. Vihola, B. Udd, L. Weiss, V. Kimonis, V. Timmerman, A. Poletti
Bicalutamide and Trehalose Ameliorate Spinal and Bulbar Muscular Atrophy Pathology in Mice
2023 M. Galbiati, M. Meroni, M. Boido, M. Cescon, P. Rusmini, V. Crippa, R. Cristofani, M. Piccolella, V. Ferrari, B. Tedesco, E. Casarotto, M. Chierichetti, M. Cozzi, F. Mina, M.E. Cicardi, S. Pedretti, N. Mitro, A. Caretto, P. Risè, A. Sala, A.P. Lieberman, P. Bonaldo, M. Pennuto, A. Vercelli, A. Poletti
Frameshift mutations in the Heat Shock Protein B8 share common pathogenic mechanisms and impair proteostasis
2022 B. Tedesco, L. Vendredy, E. Adriaenssens, M. Cozzi, B. Asselbergh, V. Crippa, R. Cristofani, P. Rusmini, V. Ferrari, E. Casarotto, M. Chierichetti, F. Mina, P. Pramaggiore, M. Galbiati, M. Piccolella, J. Baets, F. Baeke, R. De Rycke, V. Mouly, T. Laurenzi, I. Eberini, L. Weiss, V. Kimonis, V. Timmerman, A. Poletti
Mechanism of paroxetine-mediated autophagic induction in cell models of ALS/FTD
2022 B. Tedesco, P. Rusmini, V. Ferrari, V. Crippa, R. Cristofani, M. Cozzi, F. Mina, P. Pramaggiore, E. Casarotto, M. Chierichetti, M. Galbiati, M. Piccolella, A. Poletti
C9orf72 ALS/FTD dipeptide repeat protein levels are reduced by small molecules that inhibit PKA or enhance protein degradation
2022 N. V Licata, R.M. Cristofani, S. Salomonsson, K. M Wilson, L. Kempthorne, D. Vaizoglu, V. G D’Agostino, D. Pollini, R. Loffredo, M. Pancher, V. Adami, P. Bellosta, A. Ratti, G. Viero, A. Quattrone, A. M Isaacs, A. Poletti, A. Provenzani
The role of autophagy-lysosomal pathway in motor neuron diseases
2022 B. Tedesco, V. Ferrari, M. Cozzi, M. Chierichetti, E. Casarotto, P. Pramaggiore, F. Mina, M. Piccolella, R. Cristofani, V. Crippa, P. Rusmini, M. Galbiati, A. Poletti
Molecular pathways controlling unconventional non-AUG translated proteins levels in ALS and FTD.
2022 R.M. Cristofani, N. V Licata, P. Pramaggiore, V. G D’Agostino, P. Bellosta, G. Viero, A. Quattrone, A. M Isaacs, A. Poletti, A. Provenzani
Neuropathological function of the TANK1-binding kinase 1 (TBK1) in mouse models of Huntington’s disease
2022 I. Raya, Y. Douahem, D. Brenner, R. Yilmaz, R. Cristofani, A. Poletti, V. Maglione, J. Weishaupt, R. Parlato
Pathogenic variants of Valosin Containing Protein induce lysosomal damage and transcriptional activation of autophagy regulators in neuronal cells
2022 V. Ferrari, R. Cristofani, M.E. Cicardi, B. Tedesco, V. Crippa, M. Chierichetti, E. Casarotto, M. Cozzi, F. Mina, M. Galbiati, M. Piccolella, S. Carra, T. Vaccari, A. Nalbandian, V. Kimonis, T.R. Fortuna, U.B. Pandey, M.C. Gagliani, K. Cortese, P. Rusmini, A. Poletti
HSPB8 counteracts tumor activity of BRAF- and NRAS-mutant melanoma cells by modulation of RAS-prenylation and autophagy
2022 R.M. Cristofani, M. Piccolella, M. MONTAGNANI MARELLI, B. Tedesco, A. Poletti, R.M. Moretti
Insights on human small heat shock proteins and their alterations in diseases
2022 B. Tedesco, R. Cristofani, V. Ferrari, M. Cozzi, P. Rusmini, E. Casarotto, M. Chierichetti, F. Mina, M. Galbiati, M. Piccolella, V. Crippa, A. Poletti
Lysosomes Dysfunction Causes Mitophagy Impairment in PBMCs of Sporadic ALS Patients
2022 M. Bordoni, O. Pansarasa, E. Scarian, R. Cristofani, R. Leone, V. Fantini, M. Garofalo, L. Diamanti, S. Bernuzzi, S. Gagliardi, S. Carelli, A. Poletti, C. Cereda
Geldanamycin and spironolactone enhance the degradationofC9orf72ALS/FTDdipeptiderepeatproteins
2022 R. Cristofani, N. V Licata, S. Salomonsson, P. Pramaggiore, K. M Wilson, L. Kempthorne, D. Vaizoglu, V. G D'Agostino, D. Pollini, R. Loffredo, M. Pancher, V. Adami, P. Bellosta, A. Ratti, G. Viero, A. Quattrone, A. M Isaacs, A. Poletti, A. Provenzani
Neurodegenerative Disease-Associated TDP-43 Fragments Are Extracellularly Secreted with CASA Complex Proteins
2022 E. Casarotto, D. Sproviero, E. Corridori, M.C. Gagliani, M. Cozzi, M. Chierichetti, R. Cristofani, V. Ferrari, M. Galbiati, F. Mina, M. Piccolella, P. Rusmini, B. Tedesco, S. Gagliardi, K. Cortese, C. Cereda, A. Poletti, V. Crippa
The Role of Small Heat Shock Proteins in Protein Misfolding Associated Motoneuron Diseases
2022 B. Tedesco, V. Ferrari, M. Cozzi, M. Chierichetti, E. Casarotto, P. Pramaggiore, F. Mina, M. Galbiati, P. Rusmini, V. Crippa, R. Cristofani, A. Poletti
Valosin Containing Protein (VCP): A Multistep Regulator of Autophagy
2022 V. Ferrari, R. Cristofani, B. Tedesco, V. Crippa, M. Chierichetti, E. Casarotto, M. Cozzi, F. Mina, M. Piccolella, M. Galbiati, P. Rusmini, A. Poletti