CRISTOFANI, RICCARDO MARIA
CRISTOFANI, RICCARDO MARIA
Dip. di Scienze Farmacologiche e Biomolecolari Rodolfo Paoletti
VCP autophagic modulation rescues C9ORF72 pathological features in ALS-neuronal models
2024 V. Ferrari, R. Cristofani, B. Tedesco, M. Cozzi, M. Chierichetti, E. Casarotto, P. Pramaggiore, M. Piccolella, G. Patelli, L. Cornaggia, V. Crippa, M. Galbiati, P. Rusmini, A. Poletti
Shared mechanisms of pathogenicity of frameshift mutations in the heat shock protein B8 associated with neuromyopathies
2024 B. Tedesco, L. Vendredy, E. Adriaenssens, M. Cozzi, B. Asselbergh, V. Crippa, R. Cristofani, P. Rusmini, V. Ferrari, E. Casarotto, M. Chierichetti, P. Pramaggiore, M. Galbiati, M. Piccolella, L. Weiss, V. Kimonis, V. Timmerman, A. Poletti
Chaperone-assisted selective autophagy in Health and Disease
2024 B. Tedesco, E. Adriaenssens, L. Vendredy, B. Asselbergh, M. Cozzi, V. Crippa, R.M. Cristofani, P. Rusmini, V. Ferrari, E. Casarotto, M. Chierichetti, P. Pramaggiore, L. Cornaggia, G. Patelli, M. Galbiati, M. Piccolella, L. Weiss, V. Kimonis, V. Timmerman, A. Poletti
Modulating VCP to mitigate pathological mechanisms related to C9ORF72 mutation in ALS
2024 V. Ferrari, R. Cristofani, B. Tedesco, M. Cozzi, M. Chierichetti, E. Casarotto, P. Pramaggiore, A.A.M. Mohamed, L. Cornaggia, M. Piccolella, V. Crippa, M. Galbiati, P. Rusmini, A. Poletti
Effect of Hspb8 deletion in the skeletal muscle of a mouse model for Amyotrophic Lateral Sclerosis
2024 M. Galbiati, V. Crippa, P. Rusmini, R.M. Cristofani, M. Piccolella, B. Tedesco, V. Ferrari, M. Chierichetti, M. Cozzi, P. Pramaggiore, A.A.M. Mohamed, L. Cornaggia, E. Casarotto, G. Patelli, S. Dallere, V. Timmerman, M. Boido, A. Vercelli, A. Poletti
Generation of novel induced pluripotent stem cell models for the study of spinocerebellar ataxia type 17
2024 L. Cornaggia, S. Magri, P. Pramaggiore, E. Casarotto, M. Chierichetti, M. Cozzi, A. Mohamed, V. Ferrari, B. Tedesco, V. Crippa, M. Galbiati, M. Piccolella, P. Riva, P. Rusmini, D. Di Bella, F. Taroni, A. Poletti, R. Cristofani
Altered molecular and cellular mechanisms in KIF5A-associated neurodegenerative or neurodevelopmental disorders
2024 M. Cozzi, S. Magri, B. Tedesco, G. Patelli, V. Ferrari, E. Casarotto, M. Chierichetti, P. Pramaggiore, L. Cornaggia, M. Piccolella, M. Galbiati, P. Rusmini, V. Crippa, J. Mandrioli, D. Pareyson, C. Pisciotta, S. D'Arrigo, A. Ratti, L. Nanetti, C. Mariotti, E. Sarto, V. Pensato, C. Gellera, D. Di Bella, R.M. Cristofani, F. Taroni, A. Poletti
Lysosome quality control in health and neurodegenerative diseases
2024 V. Ferrari, B. Tedesco, M. Cozzi, M. Chierichetti, E. Casarotto, P. Pramaggiore, L. Cornaggia, A. Mohamed, G. Patelli, M. Piccolella, R. Cristofani, V. Crippa, M. Galbiati, A. Poletti, P. Rusmini
Identification of HSPB8 modulators counteracting misfolded protein accumulation in neurodegenerative diseases
2023 M. Chierichetti, M. Cerretani, A. Ciammaichella, V. Crippa, P. Rusmini, V. Ferrari, B. Tedesco, E. Casarotto, M. Cozzi, F. Mina, P. Pramaggiore, M. Galbiati, M. Piccolella, A. Bresciani, R. Cristofani, A. Poletti
Molecular mechanisms in KIF5A-related neurodegeneration
2023 M. Cozzi, B. Tedesco, V. Ferrari, E. Casarotto, M. Chierichetti, P. Pramaggiore, M. Piccolella, M. Galbiati, P. Rusmini, V. Crippa, C. Gellera, S. Magri, S. Santangelo, A. Ratti, R. Cristofani, F. Taroni, A. Poletti
Frameshift mutations in the heat shock protein B8 cause its aggregation and impair proteostasis in neuromyopathies
2023 B. Tedesco, L. Vendredy, E. Adriaenssens, M. Cozzi, B. Asselbergh, V. Crippa, R. Cristofani, P. Rusmini, V. Ferrari, E. Casarotto, M. Chierichetti, P. Pramaggiore, M. Galbiati, M. Piccolella, T. Laurenzi, I. Eberini, L. Weiss, V. Kimonis, V. Timmerman, A. Poletti
HSPB8 frameshift mutant aggregates weaken chaperone-assisted selective autophagy in neuromyopathies
2023 B. Tedesco, L. Vendredy, E. Adriaenssens, M. Cozzi, B. Asselbergh, V. Crippa, R. Cristofani, P. Rusmini, V. Ferrari, E. Casarotto, M. Chierichetti, F. Mina, P. Pramaggiore, M. Galbiati, M. Piccolella, J. Baets, F. Baeke, R. De Rycke, V. Mouly, T. Laurenzi, I. Eberini, A. Vihola, B. Udd, L. Weiss, V. Kimonis, V. Timmerman, A. Poletti
Bicalutamide and Trehalose Ameliorate Spinal and Bulbar Muscular Atrophy Pathology in Mice
2023 M. Galbiati, M. Meroni, M. Boido, M. Cescon, P. Rusmini, V. Crippa, R. Cristofani, M. Piccolella, V. Ferrari, B. Tedesco, E. Casarotto, M. Chierichetti, M. Cozzi, F. Mina, M.E. Cicardi, S. Pedretti, N. Mitro, A. Caretto, P. Risè, A. Sala, A.P. Lieberman, P. Bonaldo, M. Pennuto, A. Vercelli, A. Poletti
STUB1 mutants effect on TBP behavior in digenic spinocerebellar ataxia type 17
2023 P. Pramaggiore, M. Stefania, M. Chierichetti, P. Rusmini, V. Ferrari, B. Tedesco, M. Cozzi, E. Casarotto, M. Piccolella, V. Crippa, M. Galbiati, B. Daniela Di, T. Franco, A. Poletti, R.M. Cristofani
C9orf72 ALS/FTD dipeptide repeat protein levels are reduced by small molecules that inhibit PKA or enhance protein degradation
2022 N. V Licata, R.M. Cristofani, S. Salomonsson, K. M Wilson, L. Kempthorne, D. Vaizoglu, V. G D’Agostino, D. Pollini, R. Loffredo, M. Pancher, V. Adami, P. Bellosta, A. Ratti, G. Viero, A. Quattrone, A. M Isaacs, A. Poletti, A. Provenzani
Lysosomes Dysfunction Causes Mitophagy Impairment in PBMCs of Sporadic ALS Patients
2022 M. Bordoni, O. Pansarasa, E. Scarian, R. Cristofani, R. Leone, V. Fantini, M. Garofalo, L. Diamanti, S. Bernuzzi, S. Gagliardi, S. Carelli, A. Poletti, C. Cereda
Molecular pathways controlling unconventional non-AUG translated proteins levels in ALS and FTD.
2022 R.M. Cristofani, N. V Licata, P. Pramaggiore, V. G D’Agostino, P. Bellosta, G. Viero, A. Quattrone, A. M Isaacs, A. Poletti, A. Provenzani
Geldanamycin and spironolactone enhance the degradationofC9orf72ALS/FTDdipeptiderepeatproteins
2022 R. Cristofani, N. V Licata, S. Salomonsson, P. Pramaggiore, K. M Wilson, L. Kempthorne, D. Vaizoglu, V. G D'Agostino, D. Pollini, R. Loffredo, M. Pancher, V. Adami, P. Bellosta, A. Ratti, G. Viero, A. Quattrone, A. M Isaacs, A. Poletti, A. Provenzani
Neuropathological function of the TANK1-binding kinase 1 (TBK1) in mouse models of Huntington’s disease
2022 I. Raya, Y. Douahem, D. Brenner, R. Yilmaz, R. Cristofani, A. Poletti, V. Maglione, J. Weishaupt, R. Parlato
Mechanism of paroxetine-mediated autophagic induction in cell models of ALS/FTD
2022 B. Tedesco, P. Rusmini, V. Ferrari, V. Crippa, R. Cristofani, M. Cozzi, F. Mina, P. Pramaggiore, E. Casarotto, M. Chierichetti, M. Galbiati, M. Piccolella, A. Poletti