DUSETTI, IRENE
DUSETTI, IRENE
Dipartimento di Bioscienze
DUAL TARGETING OF RFAP AND FIMH IMPAIRS AIEC INTRACELLULAR SURVIVAL AND LIMITS OMV-DEPENDENT IL-23/PTH17 AXIS ACTIVATION, OFFERING A NOVEL THERAPEUTIC STRATEGY FOR CROHN¿S DISEASE
2026 I. Dusetti
Pseudomonas aeruginosa induces the generation of pathogenic IFNγ+Th17 cells that promote lung damage and chronic inflammation in cystic fibrosis
2026 I. Dusetti, G. Conte, M. Chiara, S. Puccio, D. Guidone, E. Ricciardelli, J. Cibella, M. Ronzio, D. Dolfini, E. Rossi, P. Landini, M. Ascagni, R. Orlandi, F. Damarco, A. Palleschi, A. Gramegna, F. Blasi, E. Lugli, L.J. Galietta, S. Molin, H.K. Johansen, C. Peano, M. Paroni
Pro-inflammatory intestinal Th17-cells are tissue-resident, accumulate in the epithelia in Crohn's disease, and predict unresponsiveness to vedolizumab
2026 M. Paroni, C. Faggiano, C. Righetti, I. Dusetti, V. Ranzani, G. Moschetti, D. Noviello, C. Vasco, M. Vecchi, P. Landini, F. Facciotti, S. Abrignani, F. Caprioli, J. Geginat
AIEC-derived LPS and Outer Membrane Vesicles differently drive the dysregulated immunological pathways linked to Crohn’s Disease
2025 I. Dusetti, F. Facciotti, F. Caprioli, P. Landini, A. Polissi, P. Sperandeo, M. Paroni
AIEC-dependent pTh17 cells generation relies on distinct virulence-determinants implicated in persistence and inflammatory response of intestinal epithelial cells and macrophages
2024 I. Dusetti, D. Noviello, D. Dolfini, N. Barnich, E. Billard, C. Consolandi, F. Facciotti, F. Caprioli, M. Paroni
AIEC-dependent pathogenic Th17 cell transdifferentiation in Crohn's disease is suppressed by rfaP and ybaT deletion
2024 G. Leccese, M. Chiara, I. Dusetti, D. Noviello, E. Billard, A. Bibi, G. Conte, C. Consolandi, M. Vecchi, M.P. Conte, N. Barnich, F. Caprioli, F. Facciotti, M. Paroni
Risankizumab, but not ustekinumab or vedolizumab, downregulates IL-23-induced mucosal pathogenic Th17 cells in patients with Crohn’s disease
2024 D. Noviello, I. Dusetti, V. Pivorunas, A.E. Lovati, C. Ciafardini, C. Amoroso, F. Conforti, N. Piazza O Sed, M. Vecchi, F. Facciotti, M. Paroni, F. Caprioli