| Nome |
# |
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Histone Deacetylase and Microtubules as Targets for the Synthesis of Releasable Conjugate Compounds, file dfa8b98f-0517-748b-e053-3a05fe0a3a96
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1.310
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Farinose alpine Primula species: phytochemical and morphological investigations, file dfa8b990-fc46-748b-e053-3a05fe0a3a96
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990
|
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Stimulus-responsive liposomes for biomedical applications, file dfa8b9a7-8b4b-748b-e053-3a05fe0a3a96
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766
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Chalcone Derivatives Activate and Desensitize the Transient Receptor Potential Ankyrin 1 Cation Channel, Subfamily A, Member 1 TRPA1 Ion Channel : Structure-Activity Relationships in vitro and Anti-Nociceptive and Anti-inflammatory Activity in vivo, file dfa8b999-30df-748b-e053-3a05fe0a3a96
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384
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Brown Allylation: Application to the Synthesis of Natural Products, file dfa8b9a8-c562-748b-e053-3a05fe0a3a96
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306
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Novel chemical probes for the investigation of nonribosomal peptide assembly, file dfa8b999-413c-748b-e053-3a05fe0a3a96
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264
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Cannabidiol as the Substrate in Acid-Catalyzed Intramolecular Cyclization, file dfa8b9a3-b93b-748b-e053-3a05fe0a3a96
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256
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Synthesis and biological evaluation of epothilone A dimeric compounds, file dfa8b997-8a7f-748b-e053-3a05fe0a3a96
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253
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Microtubule alterations occur early in experimental Parkinsonism and the microtubule stabilizer epothilone D is neuroprotective, file dfa8b990-a685-748b-e053-3a05fe0a3a96
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243
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2-Phenyloxazole-4-carboxamide as a Scaffold for Selective Inhibition of Human Monoamine Oxidase B, file dfa8b99f-de04-748b-e053-3a05fe0a3a96
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234
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Vincamine by synthesis and semi-synthesis, file dfa8b9a2-e949-748b-e053-3a05fe0a3a96
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223
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Cyrene: A Green Solvent for the Synthesis of Bioactive Molecules and Functional Biomaterials, file 5af020b3-79b6-41c4-9925-f633f4978b0d
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222
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Antiproliferative activity of yatein isolated from Austrocedrus chilensis against murine myeloma cells: Cytological studies and chemical investigations, file dfa8b9a1-9279-748b-e053-3a05fe0a3a96
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220
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Enzymatic kinetic resolution of 2-piperidineethanol for the enantioselective targeted and diversity oriented synthesis, file dfa8b996-c164-748b-e053-3a05fe0a3a96
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198
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Chiral flavanones from Amygdalus lycioides Spach : structural elucidation and identification of TNFalpha inhibitors by bioactivity-guided fractionation, file dfa8b998-a253-748b-e053-3a05fe0a3a96
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162
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New Insights into the Epigenetic Activities of Natural Compounds, file dfa8b99d-9079-748b-e053-3a05fe0a3a96
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160
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Catalytic C3 aza-alkylation of Indoles, file dfa8b9a2-8e57-748b-e053-3a05fe0a3a96
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156
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|
Nanolipid-trehalose conjugates and nano-assemblies as putative autophagy inducers, file dfa8b99f-a8d8-748b-e053-3a05fe0a3a96
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150
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|
Selective synthesis of methyl dithienyl-glycolates, file dfa8b99c-918c-748b-e053-3a05fe0a3a96
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146
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Structure-activity exploration of a small-molecule allosteric inhibitor of T790M/L858R double mutant EGFR, file 28fa4f7e-b31b-42dc-bcce-d9f104305c22
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136
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Studies on the Laccase-Catalyzed Oxidation of 4-Hydroxy-Chalcones, file dfa8b99f-c492-748b-e053-3a05fe0a3a96
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134
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Cannabidiol as Self-Assembly Inducer for Anticancer Drug-Based Nanoparticles, file 583ffc87-4c1a-4e62-884e-a4290f97c8f7
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130
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Structure–Activity Relationships of Hexahydrocyclopenta[c]quinoline Derivatives as Allosteric Inhibitors of CDK2 and EGFR, file dfa8b99e-cc98-748b-e053-3a05fe0a3a96
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127
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Total Synthesis of (–)-Anaferine: A Further Ramification in a Diversity-Oriented Approach, file dfa8b9a1-5834-748b-e053-3a05fe0a3a96
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121
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Total Synthesis of (‐)‐Cannabidiol‐C4, file 46de78d7-0fb8-4b07-bcb6-09964d5b2c51
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112
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Design and Synthesis of Hsp90 Inhibitors with B-Raf and PDHK1 Multi-Target Activity, file dfa8b9a9-3274-748b-e053-3a05fe0a3a96
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108
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Maytansinol Functionalization: Towards Useful Probes for Studying Microtubule Dynamics, file 8611f00d-a619-484f-b537-36562045552d
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89
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Self-assembly drug conjugates for anticancer treatment, file dfa8b99e-55a2-748b-e053-3a05fe0a3a96
|
86
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Late‐Stage Functionalisation of Pyridine‐Containing Bioactive Molecules: Recent Strategies and Perspectives, file 7096dfbf-2007-4684-a8d0-b410ef47e40a
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80
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Stereoselective Synthetic Strategies to (-)-Cannabidiol, file aea86b0a-80a6-480a-a44e-6686cec966c6
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80
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Promising Non-cytotoxic Monosubstituted Chalcones to Target Monoamine Oxidase‑B, file dfa8b9a7-8431-748b-e053-3a05fe0a3a96
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79
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A small library of chalcones induce liver cancer cell death through Akt phosphorylation inhibition, file dfa8b9a2-b660-748b-e053-3a05fe0a3a96
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77
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Combined drug action of 2-phenylimidazo[2,1-b]benzothiazole derivatives on cancer cells according to their oncogenic molecular signatures, file dfa8b9a1-2d06-748b-e053-3a05fe0a3a96
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74
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Embelin as Lead Compound for New Neuroserpin Polymerization Inhibitors, file dfa8b9a2-e39d-748b-e053-3a05fe0a3a96
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73
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Maytansinol Derivatives: Side Reactions as a Chance for New Tubulin Binders, file dfa8b9a8-a5a3-748b-e053-3a05fe0a3a96
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73
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Synthesis, Antiproliferative Effect, and Topoisomerase II Inhibitory Activity of 3-Methyl-2-phenyl-1 H-indoles, file dfa8b9a7-41a0-748b-e053-3a05fe0a3a96
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71
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Dual Functionalized Liposomes for Selective Delivery of Poorly Soluble Drugs to Inflamed Brain Regions, file f94810bd-6242-49ae-afda-675a8c5e7363
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69
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Late‐Stage Functionalisation of Pyridine‐Containing Bioactive Molecules: Recent Strategies and Perspectives, file d7391478-7012-458a-97ad-8b2d877593f8
|
67
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Stereodivergent Diversity-Oriented Synthesis: Exploiting the Versatility of 2-Piperidine Ethanol, file dfa8b99e-d0c5-748b-e053-3a05fe0a3a96
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64
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Imidazo[2,1-b]benzothiazol derivatives as potential allosteric inhibitors of the glucocorticoid receptor, file dfa8b99d-d749-748b-e053-3a05fe0a3a96
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55
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Recent advances in the development of {CB}1R selective probes, file dcb8167c-1df1-439d-b2f5-7d7af769bc0e
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54
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Heteronanoparticles by Self-Assembly of Ecdysteroid and Doxorubicin Conjugates to Overcome Cancer Resistance, file dfa8b99c-15d3-748b-e053-3a05fe0a3a96
|
54
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Design and Synthesis of New Withaferin A Inspired Hedgehog Pathway Inhibitors, file dfa8b9a8-a67a-748b-e053-3a05fe0a3a96
|
46
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|
Heteronanoparticles by self-Assembly of Doxorubicin and Cyclopamine Conjugates, file dfa8b99c-15cb-748b-e053-3a05fe0a3a96
|
45
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Synthesis of SARS-CoV-2 Mpro Inhibitors bearing a Cinnamic Ester Warhead with In Vitro Activity against Human Coronaviruses, file 6a406be0-417d-4645-b573-c956337231fd
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38
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Synthesis of Thicolchicine-Based Conjugates: Investigation towards Bivalent Tubulin/Microtubules Binders, file dfa8b99d-708f-748b-e053-3a05fe0a3a96
|
38
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|
Discovery of a Novel Trifluoromethyl Diazirine Inhibitor of SARS-CoV-2 Mpro, file 0ad0d287-7e0b-4669-9f18-5baea6edbd9f
|
30
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|
Convenient preparation and spectroscopic characterization of 7r-hydroxymatairesinol, file dfa8b9a8-aca0-748b-e053-3a05fe0a3a96
|
25
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2-Hydroxyoleic Acid as a Self-Assembly Inducer for Anti-Cancer Drug-Centered Nanoparticles, file 2bf087d9-51db-4f08-abca-09fd175f5224
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24
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Maytansinol Functionalization: Towards Useful Probes for Studying Microtubule Dynamics, file e393ed5d-11a3-40a5-9e9a-72f419d1aef3
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23
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Synthesis of potent and selective HDAC6 inhibitors led to unexpected opening of a quinazoline ring, file dfa8b9a9-ef51-748b-e053-3a05fe0a3a96
|
19
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|
Synthesis and Investigation of the G-Quadruplex Binding Properties of Kynurenic Acid Derivatives with a Dihydroimidazoquinoline-3,5-dione Core, file dfa8b9aa-57e2-748b-e053-3a05fe0a3a96
|
19
|
|
The 1,2,3-triazole ring as a bioisostere in medicinal chemistry, file dfa8b999-a79a-748b-e053-3a05fe0a3a96
|
18
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|
A small library of chalcones induce liver cancer cell death through Akt phosphorylation inhibition, file dfa8b9a2-fae6-748b-e053-3a05fe0a3a96
|
18
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Self-assembly nanoparticles of natural bioactive abietane diterpenes, file dfa8b9a8-a67b-748b-e053-3a05fe0a3a96
|
18
|
|
Synthesis and Preliminary Characterization of Putative Anle138b-Centered PROTACs against α-Synuclein Aggregation, file 4e559fab-633d-4ccd-b268-29ff557f5bd7
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17
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Chalcones and Chalcone-mimetic Derivatives as Notch Inhibitors in a Model of T-cell Acute Lymphoblastic Leukemia, file dfa8b99e-a7f1-748b-e053-3a05fe0a3a96
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17
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Design, synthesis, biological evaluation and crystal structure determination of dual modulators of carbonic anhydrases and estrogen receptors, file d97b5678-b189-448e-88c7-43a207e2a120
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16
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Folic acid functionalization for targeting self-assembled paclitaxel-based nanoparticles, file 472bf3b5-35f7-414a-be94-3cc5e3f8f3a2
|
13
|
|
Tetraphenylethylene-Based Photoluminescent Self-Assembled Nanoparticles: Preparation and Biological Evaluation, file 1da221ff-adbe-495b-b8c9-39ace426a2d6
|
12
|
|
Selective synthesis of methyl dithienyl-glycolates, file dfa8b99d-0d0e-748b-e053-3a05fe0a3a96
|
11
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Preparation of Fluorescent Tubulin Binders, file dfa8b990-98d8-748b-e053-3a05fe0a3a96
|
7
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Targeting Ovarian Cancer with Chalcone Derivatives: Cytotoxicity and Apoptosis Induction in HGSOC Cells, file a3bb0d3f-50de-4cd9-b494-1be54ef122da
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6
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Chemical approaches to targeting drug resistance in cancer stem cells, file dfa8b994-442b-748b-e053-3a05fe0a3a96
|
6
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|
Self-assembled 4-(1,2-diphenylbut-1-en-1-yl)aniline based nanoparticles: podophyllotoxin and aloin as building blocks, file dfa8b998-745e-748b-e053-3a05fe0a3a96
|
6
|
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2-Phenyloxazole-4-carboxamide as a Scaffold for Selective Inhibition of Human Monoamine Oxidase B, file dfa8b9a0-b29a-748b-e053-3a05fe0a3a96
|
6
|
|
Tools for the rational design of bivalent microtubule-targeting drugs, file dfa8b996-4459-748b-e053-3a05fe0a3a96
|
5
|
|
Microtubule-directed therapeutic strategy for neurodegenerative disorders : starting from the basis and looking on the emergences, file dfa8b998-a0d9-748b-e053-3a05fe0a3a96
|
5
|
|
Click reaction as a useful tool to creatively combine pharmacophores : the case of Vismodegib, file dfa8b995-390e-748b-e053-3a05fe0a3a96
|
4
|
|
Heteronanoparticles by self-Assembly of Doxorubicin and Cyclopamine Conjugates, file dfa8b999-73c0-748b-e053-3a05fe0a3a96
|
4
|
|
Self-Assembled squalene-based fluorescent heteronanoparticles, file dfa8b991-f7ed-748b-e053-3a05fe0a3a96
|
3
|
|
Boehmeriasin A as new lead compound for the inhibition of topoisomerases and SIRT2, file dfa8b992-1f4e-748b-e053-3a05fe0a3a96
|
3
|
|
Structure–Activity Relationships of Hexahydrocyclopenta[c]quinoline Derivatives as Allosteric Inhibitors of CDK2 and EGFR, file dfa8b99d-1493-748b-e053-3a05fe0a3a96
|
3
|
|
Self-assembling Releasable Thiocolchicine–Diphenylbutenylaniline Conjugates, file dfa8b99d-bd88-748b-e053-3a05fe0a3a96
|
3
|
|
Self-assembly drug conjugates for anticancer treatment, file dfa8b99e-53e1-748b-e053-3a05fe0a3a96
|
3
|
|
Quantitative live cell imaging of a tauopathy model enables the identification of a polypharmacological drug candidate that restores physiological microtubule interaction, file 277f6ab3-11e8-42d8-a4d7-9e55944a584f
|
2
|
|
Probing the Binding Site of Abl Tyrosine Kinase Using in Situ Click Chemistry, file dfa8b990-98dc-748b-e053-3a05fe0a3a96
|
2
|
|
Tools for the rational design of bivalent microtubule-targeting drugs, file dfa8b999-4656-748b-e053-3a05fe0a3a96
|
2
|
|
Imidazo[2,1-b]benzothiazol derivatives as potential allosteric inhibitors of the glucocorticoid receptor, file dfa8b99b-87bc-748b-e053-3a05fe0a3a96
|
2
|
|
Bruno Danieli (1939–2014), file dfa8b9a1-3fa1-748b-e053-3a05fe0a3a96
|
2
|
|
New Class of Betulinic Acid-Based Nanoassemblies of Cabazitaxel, Podophyllotoxin, and Thiocolchicine, file dfa8b9a5-1721-748b-e053-3a05fe0a3a96
|
2
|
|
Total Synthesis of (‐)‐Cannabidiol‐C4, file dfa8b9aa-65d9-748b-e053-3a05fe0a3a96
|
2
|
|
A Green Approach to Nucleophilic Aromatic Substitutions of Nicotinic Esters in Cyrene, file 154d9082-e476-4dd0-9abe-b85b33bdcfc2
|
1
|
|
A Green Approach to Nucleophilic Aromatic Substitutions of Nicotinic Esters in Cyrene, file 2023360a-3b21-4f51-af8f-874c61b69972
|
1
|
|
An efficient merging of DBU/enolate and DBU/benzyl bromide organocycles for the synthesis of alpha benzylated 1-indanone derivatives, file 24e373b4-bc9b-4ad5-adff-c572b6e3f5f7
|
1
|
|
Maytansinol Functionalization: Towards Useful Probes for Studying Microtubule Dynamics, file abbcbd53-a110-4dc5-8905-baa2661051db
|
1
|
|
Identification of new aminoacid amides containing the imidazo[2,1-b]benzothiazol-2-ylphenyl moiety as inhibitors of tumorigenesis by oncogenic Met signalling, file dfa8b993-4304-748b-e053-3a05fe0a3a96
|
1
|
|
Synthesis of (+)-Dumetorine and Congeners Using Flow Chemistry Technologies, file dfa8b994-0655-748b-e053-3a05fe0a3a96
|
1
|
|
Concise total synthesis of (+/-)-aloperine and 6-epi-aloperine, file dfa8b996-7987-748b-e053-3a05fe0a3a96
|
1
|
|
4-(1,2-diarylbut-1-en-1-yl)isobutyranilide derivatives as inhibitors of topoisomerase II, file dfa8b997-24be-748b-e053-3a05fe0a3a96
|
1
|
|
Synthesis of Pironetin-Dumetorine Hybrids as Tubulin Binders, file dfa8b997-6332-748b-e053-3a05fe0a3a96
|
1
|
|
Click synthesis of a triazole-based inhibitor of Met functions in cancer cells, file dfa8b998-91aa-748b-e053-3a05fe0a3a96
|
1
|
|
A High-throughput Screening of a Chemical Compound Library in Ovarian Cancer Stem Cells, file dfa8b99a-d080-748b-e053-3a05fe0a3a96
|
1
|
|
Stereochemistry, and complete 1 H and 13 C NMR signal assignment of C-20-oxime derivatives of posterone 2,3-acetonide in solution state, file dfa8b99b-4b2a-748b-e053-3a05fe0a3a96
|
1
|
|
Heteronanoparticles by Self-Assembly of Ecdysteroid and Doxorubicin Conjugates to Overcome Cancer Resistance, file dfa8b99b-8f07-748b-e053-3a05fe0a3a96
|
1
|
|
Synthesis of Thicolchicine-Based Conjugates: Investigation towards Bivalent Tubulin/Microtubules Binders, file dfa8b99d-cd05-748b-e053-3a05fe0a3a96
|
1
|
|
Stereodivergent Diversity-Oriented Synthesis: Exploiting the Versatility of 2-Piperidine Ethanol, file dfa8b9a0-4c2f-748b-e053-3a05fe0a3a96
|
1
|
|
Vincamine by synthesis and semi-synthesis, file dfa8b9a2-e5ed-748b-e053-3a05fe0a3a96
|
1
|
|
Engineered Ferritin Nanoparticles for the Bioluminescence Tracking of Nanodrug Delivery in Cancer, file dfa8b9a3-b429-748b-e053-3a05fe0a3a96
|
1
|
|
Stimulus-responsive liposomes for biomedical applications, file dfa8b9a7-8ec1-748b-e053-3a05fe0a3a96
|
1
|
| Totale |
9.199 |