VALSECCHI, MANUELA
VALSECCHI, MANUELA
Dipartimento di Biotecnologie Mediche e Medicina Traslazionale
GM1 structural requirements to mediate neuronal functions
2023 M. Fazzari, G. Lunghi, E. Di Biase, M. Maggioni, E.V. Carsana, L. Cioccarelli, L. Vigani, N. Loberto, M. Aureli, L. Mauri, M.G. Ciampa, M. Valsecchi, K. Takato, A. Imamura, H. Ishida, O. Ben Mariem, S. Saporiti, L. Palazzolo, E. Chiricozzi, I. Eberini, S. Sonnino
Therapeutic advantages of combined gene/cell therapy strategies in a murine model of GM2 gangliosidosis
2022 D. Sala, F. Ornaghi, F. Morena, C. Argentati, M. Valsecchi, V. Alberizzi, R. Di Guardo, A. Bolino, M. Aureli, S. Martino, A. Gritti
Glycosphingolipids
2021 E. Chiricozzi, M. Aureli, L. Mauri, E. Di Biase, G. Lunghi, M. Fazzari, M. Valsecchi, E.V. Carsana, N. Loberto, A.E.G. Prinetti, A. Sandro Sonnino
APOL1 polymorphism modulates sphingolipid profile of human podocytes
2020 M. Valsecchi, V. Cazzetta, F. Oriolo, X. Lan, R. Piazza, M.A. Saleem, P.C. Singhal, D. Mavilio, J. Mikulak, M. Aureli
Novel bicistronic lentiviral vectors correct beta-Hexosaminidase deficiency in neural and hematopoietic stem cells and progeny: implications for in vivo and ex vivo gene therapy of GM2 gangliosidosis
2020 F. Ornaghi, D. Sala, F. Tedeschi, M.C. Maffia, M. Bazzucchi, M. Ciofetti, M. Valsecchi, M. Aureli, S. Martino, A. Gritti
Gangliosides in the differentiation process of primary neurons: the specific role of GM1-oligosaccharide
2020 E. Di Biase, G. Lunghi, M. Fazzari, M. Maggioni, D.Y. Pomè, M. Valsecchi, M. Samarani, P. Fato, M.G. Ciampa, S. Prioni, L. Mauri, S. Sonnino, E. Chiricozzi
Parkinson's disease recovery by GM1 oligosaccharide treatment in the B4galnt1+/- mouse model
2019 E. Chiricozzi, L. Mauri, G. Lunghi, E. Di Biase, M. Fazzari, M. Maggioni, M. Valsecchi, S. Prioni, N. Loberto, D.Y. Pomè, M.G. Ciampa, P. Fato, G. Verlengia, S. Cattaneo, R. Assini, G. Wu, S. Alselehdar, R.W. Ledeen, S. Sonnino
ASAH1 variant causing a mild SMA phenotype with no myoclonic epilepsy : a clinical, biochemical and molecular study
2016 M. Filosto, M. Aureli, B. Castellotti, F. Rinaldi, D. Schiumarini, M. Valsecchi, S. Lualdi, R. Mazzotti, V. Pensato, S. Rota, C. Gellera, M. Filocamo, A. Padovani
IPSC-derived neurons from GBA1-associated Parkinson's disease patients show autophagic defects and impaired calcium homeostasis
2014 D.C. Schöndorf, M. Aureli, F.E. Mcallister, C.J. Hindley, F. Mayer, B. Schmid, S.P. Sardi, M. Valsecchi, S. Hoffmann, L.K. Schwarz, U. Hedrich, D. Berg, L.S. Shihabuddin, J. Hu, J. Pruszak, S.P. Gygi, S. Sonnino, T. Gasser, M. Deleidi
Ceramides as possible nutraceutical compounds : characterization of the ceramides of the moro blood orange (citrus sinensis)
2012 M. Valsecchi, L. Mauri, R. Casellato, M.G. Ciampa, L. Rizza, A. Bonina, F. Bonina, S. Sonnino
Role of gangliosides and Plasma Membrane-Associated Sialidase in the Process of Cell Membrane Organization
2011 S. Sonnino, V. Chigorno, M. Aureli, A.P. Masilamani, M. Valsecchi, N. Loberto, S. Prioni, L. Mauri, A.E.G. Prinetti
Aberrant Glycosphingolipid Expression and Mambrane Organization in Tumor Cells : Consequences on Tumor-Host Interactions
2011 A. Prinetti, S. Prioni, N. Loberto, M. Aureli, V. Nocco, G. Illuzzi, L. Mauri, M. Valsecchi, V. Chigorno, S. Sonnino
Sphingosine kinase mediates resistance to the synthetic retinoid N-(4-hydroxyphenyl)retinamide in human ovarian cancer cells
2010 G. Illuzzi, C. Bernacchioni, M. Aureli, S. Prioni, G. Frera, C. Donati, M. Valsecchi, V. Chigorno, P. Bruni, S. Sonnino, A. Prinetti
Sphingolipidomics af A2780 human ovarian carcinoma cells treated with synthetic retinoids
2010 M. Valsecchi, M. Aureli, L. Mauri, V.L. Chigorno, A.E.G. Prinetti, S. Sonnino
Altered sphingolipid metabolism in acidic sphingomyelinase knockout mice, an animal model for Niemann-Pick disease type A
2009 A.E.G. Prinetti, B. Buccinnà, M. Piccinini, F. Scandroglio, S. Prioni, M. Valsecchi, E. Lupino, C. Ramondetti, S. Sonnino, M.T. Rinaudo
Alterations of protein and lipid patterns in brain white matter of ASMKO mice, the animal model of Niemann-Pick disease type A
2009 M. Piccinini, B. Buccinnà, A.E.G. Prinetti, F. Scandroglio, S. Prioni, M. Valsecchi, E. Lupino, C. Ramondetti, S. Sonnino, M.T. Rinaudo
Neural precursor cell cultures from GM2-gangliosidosis animal models recapitulate the biochemical and molecular hallmarks of the brain pathology
2009 S. Martino, I. Di Girolamo, C. Cavazzin, R. Tiribuzi, R. Galli, A. Rivaroli, M. Valsecchi, K. Sandhoff, S. Sonnino, A. Vescovi, A. Gritti, A. Orlacchio
Thin layer chromatography of gangliosides
2009 F. Scandroglio, N. Loberto, M. Valsecchi, V.L. Chigorno, A.E.G. Prinetti, S. Sonnino
Application of oligosaccharidic gold nanoparticles to the vaccines for the therapy of brest cancer: synthesis of Neu5Gc-lactose antigen starting from a complex ganglioside mixture
2009 F.C.V. Ronchetti, M. Valsecchi, R. Casellato, M.G. Ciampa, L. Mauri, S. Sonnino
Deregulated sphingolipid metabolism in neurodegenerative disorders: lessons from acidic sphingomyelinase knockout mice, an animal model for Niemann-Pick disease type A
2009 A.E.G. Prinetti, M. Piccinini, B. Buccinnà, F. Scandroglio, S. Prioni, M. Valsecchi, A. Lomartire, E. Lupino, C. Ramondetti, M.T. Rinaudo, S. Sonnino