CONTI, PAOLA
CONTI, PAOLA
Dipartimento di Scienze Farmaceutiche
Chemo-enzymatic flow synthesis of nature-inspired phenolic carbonates and carbamates as antiradical and antimicrobial agents
2024 S. Vicinanza, L. Mombelli, F. Annunziata, S. Donzella, M.L. Contente, C. Borsari, P. Conti, G. Meroni, F. Molinari, P.A.M. Martino, A. Pinto, L. Tamborini
Effect of glycosylation on the affinity of the MTB protein Ag85B for specific antibodies: towards the design of a dual-acting vaccine against tuberculosis
2024 R. Bernardini, S. Tengattini, Z. Li, L. Piubelli, T. Bavaro, A.B. Modolea, M. Mattei, P. Conti, S. Marini, Y. Zhang, L. Pollegioni, C. Temporini, M. Terreni
Role of Stereochemistry on the Biological Activity of Nature-Inspired 3-Br-Acivicin Isomers and Derivatives
2023 A. Galbiati, A. Zana, C. Borsari, M. Persico, S. Bova, O. Tkachuk, A.I. Corfu, L. Tamborini, N. Basilico, C. Fattorusso, S. Bruno, S. Parapini, P. Conti
Understanding Intrinsic Warhead Reactivity and Cysteine Druggability in Covalent Drug Discovery
2023 C. Borsari, A. Corfu, P. Conti
Discovery of a spirocyclic 3-bromo-4,5-dihydroisoxazole covalent inhibitor of hGAPDH with antiproliferative activity against pancreatic cancer cells
2023 A. Galbiati, S. Bova, R. Pacchiana, C. Borsari, M. Persico, A. Zana, S. Bruno, M. Donadelli, C. Fattorusso, P. Conti
Enzymatic continuous-flow preparation of nature-inspired phenolic esters as antiradical and antimicrobial noagents
2022 F. Annunziata, M.L. Contente, V. Anzi, S. Donzella, P. Conti, F. Molinari, P.A. Martino, G. Meroni, V.M. Sora, L. Tamborini, A. Pinto
3-Bromo-Isoxazoline Derivatives Inhibit GAPDH Enzyme in PDAC Cells Triggering Autophagy and Apoptotic Cell Death
2022 R. Pacchiana, N. Mullappilly, A. Pinto, S. Bova, S. Forciniti, G. Cullia, E. Dalla Pozza, E. Bottani, I. Decimo, I. Dando, S. Bruno, P. Conti, M. Donadelli
Continuous-flow stereoselective reduction of prochiral ketones in a whole cell bioreactor with natural deep eutectic solvents
2022 F. Annunziata, A. Guaglio, P. Conti, L. Tamborini, R. Gandolfi
Design of a fully automated system for the synthesis of pharmaceutically relevant building blocks exploiting immobilized Rhodotorula rubra and new solvent systems
2021 F. Annunziata, A. Guaglio, P. Conti, R. Gandolfi, L. Tamborini
Development of Potent 3-Br-isoxazoline-Based Antimalarial and Antileishmanial Compounds
2021 A. Galbiati, A. Zana, C. Coser, L. Tamborini, N. Basilico, S. Parapini, D. Taramelli, P. Conti
Immobilized enzyme reactors based on nucleoside phosphorylases and 2′-deoxyribosyltransferase for the in-flow synthesis of pharmaceutically relevant nucleoside analogues
2020 F. Rinaldi, J. Fernandez-Lucas, D. de la Fuente, C. Zheng, T. Bavaro, B. Peters, G. Massolini, F. Annunziata, P. Conti, I. de la Mata, M. Terreni, E. Calleri
Covalent inhibitors of GAPDH : From unspecific warheads to selective compounds
2020 A. Galbiati, A. Zana, P. Conti
Use of Immobilized Amine Transaminase from Vibrio fluvialis under Flow Conditions for the Synthesis of (S)-1-(5-Fluoropyrimidin-2-yl)-ethanamine
2020 R. Semproli, G. Vaccaro, E.E. Ferrandi, M. Vanoni, T. Bavaro, G. Marrubini, F. Annunziata, P. Conti, G. Speranza, D. Monti, L. Tamborini, D. Ubiali
Identification of a 2,4-diaminopyrimidine scaffold targeting Trypanosoma brucei pteridine reductase 1 from the LIBRA compound library screening campaign
2020 P. Linciano, G. Cullia, C. Borsari, M. Santucci, S. Ferrari, G. Witt, S. Gul, M. Kuzikov, B. Ellinger, N. Santarem, A. Cordeiro da Silva, P. Conti, M.L. Bolognesi, M. Roberti, F. Prati, F. Bartoccini, M. Retini, G. Piersanti, A. Cavalli, L. Goldoni, S.M. Bertozzi, F. Bertozzi, E. Brambilla, V. Rizzo, D. Piomelli, A. Pinto, T. Bandiera, M.P. Costi
An enzymatic flow-based preparative route to vidarabine
2020 L. Tamborini, C. Previtali, F. Annunziata, T. Bavaro, M. Terreni, E. Calleri, F. Rinaldi, A. Pinto, G. Speranza, D. Ubiali, P. Conti
An innovative synthesis of the antiviral Vidarabine through the dual use of flow chemistry and biocatalysis
2019 F. Annunziata, C. Previtali, E. Calleri, F. Rinaldi, T. Bavaro, G. Speranza, P. Conti, D. Ubiali, L. Tamborini
Inhibition of SIRT1 deacetylase and p53 activation uncouples the anti-inflammatory and chemopreventive actions of NSAIDs
2019 G. Dell'Omo, D. Crescenti, C. Vantaggiato, C. Parravicini, A.P. Borroni, N. Rizzi, M. Garofalo, A. Pinto, C. Recordati, E. Scanziani, F.D. Bassi, G. Pruneri, P. Conti, I. Eberini, A. Maggi, P. Ciana
Covalent Inhibitors of Plasmodium falciparum Glyceraldehyde 3-Phosphate Dehydrogenase with Antimalarial Activity in Vitro
2019 G. Cullia, S. Bruno, S. Parapini, M. Margiotta, L. Tamborini, A. Pinto, A. Galbiati, A. Mozzarelli, M. Persico, A. Paladino, C. Fattorusso, D. Taramelli, P. Conti
Development of an integrated chromatographic system for ω-transaminase-IMER characterization useful for flow-chemistry applications
2019 M. Corti, F. Rinaldi, D. Monti, E.E. Ferrandi, G. Marrubini, C. Temporini, G. Tripodo, T. Kupfer, P. Conti, M. Terreni, G. Massolini, E. Calleri
Folates in Trypanosoma brucei: achievements and opportunities
2018 G. Cullia, L. Tamborini, P. Conti, C. De Micheli, A. Pinto