Objectives: To compare whole body-MRI (WB-MRI) with diffusion-weighted imaging and FDG-PET/CT in staging newly diagnosed FDG-avid lymphomas.Methods: 68 patients (37 males, 31 females; median age 42 years; range 15-86 years) with histologically confirmed lymphoma (37 Classical Hodgkin, 16 Diffuse large B-cell, 10 Follicular, 5 Mantle cell) underwent both MRI and FDG-PET/CT before treatment. Ann Arbor stages obtained with WB-MRI and FDG-PET/CT were compared using Cohen's k statistics. Moreover WB-MRI and FDG-PET/CT stages were compared with the pathological stages obtained after the diagnostic iter using also bone marrow and available biopsies if clinically indicated.Results: The agreement between WB-MRI and FDG-PET/CT was excellent. WB-MRI stage was equal to those of FDG-PET/CT in 62168 patients (91.2%). There was an excellent agreement between WB-MRI stage and pathological stage (63168 patients; 92.6%), and between FDG-PET/CT and pathological stage (64168 patients; 94.1%). The differences between the stages were more frequent in the patients with Mantle cell lymphoma.Conclusions: WB-MRI can be considered as a promising technique for FDG-avid lymphoma staging.
Comparison between whole-body MRI with diffusion-weighted imaging and PET/CT in staging newly diagnosed FDG-avid lymphomas / D. Albano, C. Patti, L. La Grutta, F. Agnello, E. Grassedonio, A. Mulè, G. Cannizzaro, U. Ficola, R. Lagalla, M. Midiri, M. Galia. - In: EUROPEAN JOURNAL OF RADIOLOGY. - ISSN 0720-048X. - 85:2(2016 Feb), pp. 313-318. [10.1016/j.ejrad.2015.12.006]
Comparison between whole-body MRI with diffusion-weighted imaging and PET/CT in staging newly diagnosed FDG-avid lymphomas
D. Albano
Primo
;A. Mulè;
2016
Abstract
Objectives: To compare whole body-MRI (WB-MRI) with diffusion-weighted imaging and FDG-PET/CT in staging newly diagnosed FDG-avid lymphomas.Methods: 68 patients (37 males, 31 females; median age 42 years; range 15-86 years) with histologically confirmed lymphoma (37 Classical Hodgkin, 16 Diffuse large B-cell, 10 Follicular, 5 Mantle cell) underwent both MRI and FDG-PET/CT before treatment. Ann Arbor stages obtained with WB-MRI and FDG-PET/CT were compared using Cohen's k statistics. Moreover WB-MRI and FDG-PET/CT stages were compared with the pathological stages obtained after the diagnostic iter using also bone marrow and available biopsies if clinically indicated.Results: The agreement between WB-MRI and FDG-PET/CT was excellent. WB-MRI stage was equal to those of FDG-PET/CT in 62168 patients (91.2%). There was an excellent agreement between WB-MRI stage and pathological stage (63168 patients; 92.6%), and between FDG-PET/CT and pathological stage (64168 patients; 94.1%). The differences between the stages were more frequent in the patients with Mantle cell lymphoma.Conclusions: WB-MRI can be considered as a promising technique for FDG-avid lymphoma staging.File | Dimensione | Formato | |
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