We compared 19,207 cases of SARS-CoV-2 variant B.1.1.7/S gene target failure (SGTF), 436 B.1.351 and 352 P.1 to non-variant cases reported by seven European countries. COVID-19 cases with these variants had significantly higher adjusted odds ratios for hospitalisation (B.1.1.7/SGTF: 1.7, 95% confidence interval (CI): 1.0-2.9; B.1.351: 3.6, 95% CI: 2.1-6.2; P.1: 2.6, 95% CI: 1.4-4.8) and B.1.1.7/SGTF and P.1 cases also for intensive care admission (B.1.1.7/SGTF: 2.3, 95% CI: 1.4-3.5; P.1: 2.2, 95% CI: 1.7-2.8).

Characteristics of SARS-CoV-2 variants of concern B.1.1.7, B.1.351 or P.1: data from seven EU/EEA countries, weeks 38/2020 to 10/2021 / T. Funk, A. Pharris, G. Spiteri, N. Bundle, A. Melidou, M. Carr, G. Gonzalez, A. Garcia-Leon, F. Crispie, L. O'Connor, N. Murphy, J. Mossong, A. Vergison, A.K. Wienecke-Baldacchino, T. Abdelrahman, F. Riccardo, P. Stefanelli, A. Di Martino, A. Bella, A. Lo Presti, P. Casaca, J. Moreno, V. Borges, J. Isidro, R. Ferreira, J.P. Gomes, L. Dotsenko, H. Suija, J. Epstein, O. Sadikova, H. Sepp, N. Ikonen, C. Savolainen-Kopra, S. Blomqvist, T. Mottonen, O. Helve, J. Gomes-Dias, C. Adlhoch, G. Macori, L. Russell, Z. Yandle, C. Bennett, E. O'Byrne, A. Murphy, G. Tuite, A. Conroy, M. Duffy, U. Morley, B. Keoghan, I. Ford, M. Kennedy, S. Mcdonnell, A. Flynn, A. Clarke, A. Crowley, C. Martin, E. Kelly, J. Foxton, D. Hare, L. Dunford, J. Connell, J. Moran, J. Dean, S. Fanning, L. Rajan, C. De Gascun, J. Kenny, P. Cotter, C. Walsh, E. Lawton, A. Fitzpatrick, E. Mullins, M. Della Bartola, M. Mccabe, P. Stapleton, C. Meaney, L. Fanning, M. Prentice, J. Macsharry, C. Dempsey, P. Mallon, A. Leon, A. Chaturvedi, S. Coughlan, G. Mcandrew, K. Reddington, F. Walsh, D. Fitzpatrick, C. Smyth, T. O'Dwyer, T. Chambers, L. Clarke, D. Jebb, J. Klopp, D. Kavanagh, K. Haslam, P. Buckley, K. Lemass, F. Fitzpatrick, K. Burns, J. Cafferkey, A. Richmond, M. Foley, J. Sanchez-Morgado, S. Chalapati, N. Pinnamaneni, C. Crosbie, D. Limbachiya, W. Tinago, A.A. Garcia Leon, S. Miles, D. Alalwan, R. Negi, A. Macken, E. Feeney, G. Kenny, K. Mccann, N. Kelly, M. Blair, R. Mccann, C. Kenny, C. O'Brion, S. Waqas, S. Savinelli, P. Doran, T. Bracken, P. Varghese, J.S. Lambert, A. Cotter, E. Muldoon, G. Sheehan, T. Mcginty, J. Lambert, S. Green, K. Leamy, E. de Barra, S. Mcconkey, C. Kelly, M. Horgan, C. Sadlier, O. Yousif, J. O'Donnell, M. Fitzgerald, N. Petty-Saphon, J. Cuddihy, S. Fiore, C. Fabiani, E. Benedetti, G. Di Mario, M. Facchini, S. Puzelli, L. Calzoletti, S. Fontana, G. Venturi, C. Fortuna, G. Marsili, A. Amendola, L. Stuppia, G. Savini, A. Picerno, T. Lopizzo, D. Dell'Edera, P. Minchella, F. Greco, M.V. Mauro, G. Viglietto, L. Atripaldi, A. Limone, P. D'Agaro, D. Licastro, A. Marcello, M.R. Capobianchi, G. Icardi, B. Bruzzone, F. Lillo, A. Orsi, E. Pariani, F. Baldanti, M.R. Gismondo, F. Maggi, A. Caruso, F. Ceriotti, B. Boniotti, P. Bagnarelli, S. Garofalo, M. Scutella, E. Pagani, L. Collini, V. Ghisetti, G. Ru, M. Chironna, A. Parisi, S. Rubino, C. Serra, G. Piras, F. Coghe, F. Vitale, F. Tramuto, G. Scalia, C.I. Palermo, G. Mancuso, F. Di Gaudio, S. Vullo, S. Reale, M.G. Cusi, G.M. Rossolini, M. Pistello, A. Mencacci, B. Camilloni, S. Severini, M. Di Benedetto, T. Calogero, I. Monne, V. Biscaro. - In: EUROSURVEILLANCE. - ISSN 1560-7917. - 26:16(2021), pp. 2100348.1-2100348.10. [10.2807/1560-7917.ES.2021.26.16.2100348]

Characteristics of SARS-CoV-2 variants of concern B.1.1.7, B.1.351 or P.1: data from seven EU/EEA countries, weeks 38/2020 to 10/2021

E. Pariani;M.R. Gismondo;
2021

Abstract

We compared 19,207 cases of SARS-CoV-2 variant B.1.1.7/S gene target failure (SGTF), 436 B.1.351 and 352 P.1 to non-variant cases reported by seven European countries. COVID-19 cases with these variants had significantly higher adjusted odds ratios for hospitalisation (B.1.1.7/SGTF: 1.7, 95% confidence interval (CI): 1.0-2.9; B.1.351: 3.6, 95% CI: 2.1-6.2; P.1: 2.6, 95% CI: 1.4-4.8) and B.1.1.7/SGTF and P.1 cases also for intensive care admission (B.1.1.7/SGTF: 2.3, 95% CI: 1.4-3.5; P.1: 2.2, 95% CI: 1.7-2.8).
COVID-19; Europe; SARS-CoV-2; surveillance; variants of concern
Settore MED/42 - Igiene Generale e Applicata
2021
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2434/990208
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