AimsRing annuloplasty is the gold standard of surgical repair in degenerative mitral valve disease. However, prosthetic annuloplasty has some drawbacks and potential hazards. Suture annuloplasty theoretically is able to preserve annular leaflet dynamics and left ventricular performance, but experience is limited. The aim of the study was to review the early and long-term outcome of the posterior double-suture annuloplasty (DSA) technique for degenerative mitral valve repair.MethodsFrom January 2002 to December 2008, 400 patients underwent primary mitral valve repair for degenerative disease either with posterior DSA [n=147 (37%)] or with flexible posterior annuloplasty band [n=253 (63%)]. Differences in patient characteristics were addressed by propensity-score matching (132 pairs). A composite end-point of mitral valve failure (MVF) was calculated as the incidence of mitral valve regurgitation greater than 2+ or need for mitral valve replacement at follow-up.ResultsAfter propensity-score matching, the distribution of preoperative variables among matched pairs was, on average, equal. Isolated annuloplasty and leaflet repair techniques were similarly performed in both groups (P=0.20). In-hospital mortality was comparable between the two study groups (P=0.48). Predischarge echocardiography showed excellent results regarding valve hemodynamics (P=0.71). At a mean follow-up of 113 years, all-cause mortality (P=0.12), need for mitral valve replacement (P=0.49), and cardiac re-hospitalization rate (P=0.57) resulted comparable between the two groups. Ten-year survival (75 vs. 71%, P=0.51) and freedom from MVF (92 vs. 84%, P=0.39) were similar between posterior annuloplasty band and DSA groups.ConclusionSuture annuloplasty demonstrated comparable results with posterior flexible band repair and could be a viable option for mitral valve surgery in selected patients, such as in the minimally invasive approach, in endocarditis, and in developing countries.

Long-term results of suture annuloplasty for degenerative mitral valve disease: a propensity-matched analysis / A. Garatti, A. Canziani, A. Parolari, S. Castelvecchio, M. Guazzi, A. Daprati, A.A. Farah, F. Grimaldi, S. Tripepi, L. Menicanti. - In: JOURNAL OF CARDIOVASCULAR MEDICINE. - ISSN 1558-2027. - 19:1(2018 Jan), pp. 22-28. [10.2459/JCM.0000000000000608]

Long-term results of suture annuloplasty for degenerative mitral valve disease: a propensity-matched analysis

A. Garatti
;
A. Parolari;M. Guazzi;A. Daprati;
2018

Abstract

AimsRing annuloplasty is the gold standard of surgical repair in degenerative mitral valve disease. However, prosthetic annuloplasty has some drawbacks and potential hazards. Suture annuloplasty theoretically is able to preserve annular leaflet dynamics and left ventricular performance, but experience is limited. The aim of the study was to review the early and long-term outcome of the posterior double-suture annuloplasty (DSA) technique for degenerative mitral valve repair.MethodsFrom January 2002 to December 2008, 400 patients underwent primary mitral valve repair for degenerative disease either with posterior DSA [n=147 (37%)] or with flexible posterior annuloplasty band [n=253 (63%)]. Differences in patient characteristics were addressed by propensity-score matching (132 pairs). A composite end-point of mitral valve failure (MVF) was calculated as the incidence of mitral valve regurgitation greater than 2+ or need for mitral valve replacement at follow-up.ResultsAfter propensity-score matching, the distribution of preoperative variables among matched pairs was, on average, equal. Isolated annuloplasty and leaflet repair techniques were similarly performed in both groups (P=0.20). In-hospital mortality was comparable between the two study groups (P=0.48). Predischarge echocardiography showed excellent results regarding valve hemodynamics (P=0.71). At a mean follow-up of 113 years, all-cause mortality (P=0.12), need for mitral valve replacement (P=0.49), and cardiac re-hospitalization rate (P=0.57) resulted comparable between the two groups. Ten-year survival (75 vs. 71%, P=0.51) and freedom from MVF (92 vs. 84%, P=0.39) were similar between posterior annuloplasty band and DSA groups.ConclusionSuture annuloplasty demonstrated comparable results with posterior flexible band repair and could be a viable option for mitral valve surgery in selected patients, such as in the minimally invasive approach, in endocarditis, and in developing countries.
echocardiography; mitral valve disease; mitral valve repair; Cardiology and Cardiovascular Medicine
Settore MED/23 - Chirurgia Cardiaca
Settore MED/11 - Malattie dell'Apparato Cardiovascolare
Settore MED/11 - Malattie dell'Apparato Cardiovascolare
gen-2018
Article (author)
File in questo prodotto:
File Dimensione Formato  
Long_term_results_of_suture_annuloplasty_for.4.pdf

accesso riservato

Descrizione: Original article
Tipologia: Publisher's version/PDF
Dimensione 176.99 kB
Formato Adobe PDF
176.99 kB Adobe PDF   Visualizza/Apri   Richiedi una copia
Pubblicazioni consigliate

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2434/981208
Citazioni
  • ???jsp.display-item.citation.pmc??? 2
  • Scopus 4
  • ???jsp.display-item.citation.isi??? 4
social impact