The structure and properties of a group of gangliosides modified by mild alkaline treatment are discussed. We will present the occurrence and the structure of gangliosides carrying the N-acetyneuraminic acid O-acetylated in position 9, the Neu5,9Ac(2), and of gangliosides carrying a sialic acid that forms a lactone ring. Starting from biochemical data we will discuss the possible biochemical role played by these gangliosides in the processes of cell signaling and maintenance of brain functions.

Alkali-labile gangliosides / L. Mauri, S. Sonnino. - In: GLYCOCONJUGATE JOURNAL. - ISSN 0282-0080. - 40:3(2023 Jun), pp. 269-276. [10.1007/s10719-023-10103-0]

Alkali-labile gangliosides

L. Mauri
Primo
;
S. Sonnino
Ultimo
2023

Abstract

The structure and properties of a group of gangliosides modified by mild alkaline treatment are discussed. We will present the occurrence and the structure of gangliosides carrying the N-acetyneuraminic acid O-acetylated in position 9, the Neu5,9Ac(2), and of gangliosides carrying a sialic acid that forms a lactone ring. Starting from biochemical data we will discuss the possible biochemical role played by these gangliosides in the processes of cell signaling and maintenance of brain functions.
Settore BIO/10 - Biochimica
giu-2023
25-gen-2023
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2434/967333
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