The emergency caused by Covid-19 pandemic raised interest in studying lifestyles and comorbidities as important determinants of poor Covid-19 prognosis. Data on tobacco smoking, alcohol consumption and obesity are still limited, while no data are available on the role of e-cigarettes and heated tobacco products (HTP). To clarify the role of tobacco smoking and other lifestyle habits on COVID-19 severity and progression, we designed a longitudinal observational study titled COvid19 and SMOking in ITaly (COSMO-IT). About 30 Italian hospitals in North, Centre and South of Italy joined the study. Its main aims are: 1) to quantify the role of tobacco smoking and smoking cessation on the severity and progression of COVID-19 in hospitalized patients; 2) to compare smoking prevalence and severity of the disease in relation to smoking in hospitalized COVID-19 patients versus patients treated at home; 3) to quantify the association between other lifestyle factors, such as e-cigarette and HTP use, alcohol and obesity and the risk of unfavourable COVID-19 outcomes. Socio-demographic, lifestyle and medical history information will be gathered for around 3000 hospitalized and 700-1000 home-isolated, laboratory-confirmed, COVID-19 patients. Given the current absence of a vaccine against SARS-COV-2 and the lack of a specific treatment for -COVID-19, prevention strategies are of extreme importance. This project, designed to highly contribute to the international scientific debate on the role of avoidable lifestyle habits on COVID-19 severity, will provide valuable epidemiological data in order to support important recommendations to prevent COVID-19 incidence, progression and mortality.
Covid-19 and the role of smoking: the protocol of the multicentric prospective study COSMO-IT (COvid19 and SMOking in ITaly) / M.S. Cattaruzza, G. Gorini, C. Bosetti, R. Boffi, A. Lugo, C. Veronese, G. Carreras, C. Santucci, C. Stival, R. Pacifici, V. Zagà, S. Gallus, F. Giulietti, R. Sarzani, F. Spannella, M. Del Donno, S. Tartaglione, G. Marrazzo, G. Pelaia, V. D’Agosto, A. Berti, F. Voller, S. Cardellicchio, C. Cresci, M.P. Foschino Barbaro, R. De Palma, S. Negrini, V. Sicbaldi, A. Serafini, M. Bisconti, L. Refolo, G. Landoni, P. Rovere, G. Veronesi, P. Faverio, W. Garavello, A. Pesci, R. Giacobbe, P. Martucci, R. Parrella, F. Scarano, M. Aiello, A. Chetta, C. Franco, A. Mangia, L. Carrozzi, F.F. Maggi Monzani, F. Pistelli, P. Russo, A. Sanna, F.M. Barreca, V. Conti, E. Rossi, M. Ruli, S. Ruli, S.E. Varzaneh, R. Principe, S. Guerrini, A. Sebastiani, G. Galluccio, A. Pezzuto, A. Ricci, E. Casali, C. Mastroianni, P. Pirina, F. Polo, F. Beatrice, M. Romagnoli, M. Baraldo, P.G. Cojutti, E. Graziano, D. Pecori, C. Tascini, B. Tinghino. - In: ACTA BIOMEDICA. - ISSN 2531-6745. - 91:3(2020 Aug 27), pp. e2020062.1-e2020062.6. [10.23750/abm.v91i3.10373]
Covid-19 and the role of smoking: the protocol of the multicentric prospective study COSMO-IT (COvid19 and SMOking in ITaly)
C. Santucci;
2020
Abstract
The emergency caused by Covid-19 pandemic raised interest in studying lifestyles and comorbidities as important determinants of poor Covid-19 prognosis. Data on tobacco smoking, alcohol consumption and obesity are still limited, while no data are available on the role of e-cigarettes and heated tobacco products (HTP). To clarify the role of tobacco smoking and other lifestyle habits on COVID-19 severity and progression, we designed a longitudinal observational study titled COvid19 and SMOking in ITaly (COSMO-IT). About 30 Italian hospitals in North, Centre and South of Italy joined the study. Its main aims are: 1) to quantify the role of tobacco smoking and smoking cessation on the severity and progression of COVID-19 in hospitalized patients; 2) to compare smoking prevalence and severity of the disease in relation to smoking in hospitalized COVID-19 patients versus patients treated at home; 3) to quantify the association between other lifestyle factors, such as e-cigarette and HTP use, alcohol and obesity and the risk of unfavourable COVID-19 outcomes. Socio-demographic, lifestyle and medical history information will be gathered for around 3000 hospitalized and 700-1000 home-isolated, laboratory-confirmed, COVID-19 patients. Given the current absence of a vaccine against SARS-COV-2 and the lack of a specific treatment for -COVID-19, prevention strategies are of extreme importance. This project, designed to highly contribute to the international scientific debate on the role of avoidable lifestyle habits on COVID-19 severity, will provide valuable epidemiological data in order to support important recommendations to prevent COVID-19 incidence, progression and mortality.
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