The majority of the 22 cohort studies and 46 case-control studies showed no associations. Some risks for bladder, pancreas and hematopoietic cancers found in a few studies were not confirmed in other studies. Based on the review of both the experimental data on genotoxicity or carcinogenicity of the specific NSS evaluated, and the epidemiological studies it can be concluded that there is no evidence of cancer risk associated to NSS consumption.
Non-sugar sweeteners and cancer: toxicological and epidemiological evidence / S. Pavanello, A. Moretto, C. La Vecchia, G. Alicandro. - In: REGULATORY TOXICOLOGY AND PHARMACOLOGY. - ISSN 0273-2300. - 139:(2023 Mar 03), pp. 105369.1-105369.16. [10.1016/j.yrtph.2023.105369]
Non-sugar sweeteners and cancer: toxicological and epidemiological evidence
C. La VecchiaPenultimo
;G. AlicandroUltimo
2023
Abstract
The majority of the 22 cohort studies and 46 case-control studies showed no associations. Some risks for bladder, pancreas and hematopoietic cancers found in a few studies were not confirmed in other studies. Based on the review of both the experimental data on genotoxicity or carcinogenicity of the specific NSS evaluated, and the epidemiological studies it can be concluded that there is no evidence of cancer risk associated to NSS consumption.
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Non sugar sweewteners proofs_Pavanello_S.pdf
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1-s2.0-S0273230023000375-main.pdf
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