The paper investigates the use of poly(1-vinylpyrrolidone-co-2-dimethylaminoethylmetacrilate) (PVP-co-DMAEMA) as a novel coating agent in the preparation of alginate-based microcapsule for the supplement delivery of probiotics. Probiotic Lactobacillus plantarum is used to study the viability of the encapsulated bacterium when exposed to conditions simulating the gastrointestinal tract and industrial process. Results demonstrate that the PVP-co-DMAEMA polymer constitutes a pH-responsive coating suitable for probiotic supplement delivery.
PVP-co-DMAEMA as Novel Polymeric Coating Material for Probiotic Supplements Delivery / G. D'Orazio, A. De Giani, J. Zampolli, Z. Zeaiter, P. Di Gennaro, B. La Ferla. - In: MACROMOLECULAR CHEMISTRY AND PHYSICS. - ISSN 1022-1352. - 220:21(2019 Nov), pp. 1900291.1-1900291.4. [10.1002/macp.201900291]
PVP-co-DMAEMA as Novel Polymeric Coating Material for Probiotic Supplements Delivery
G. D'OrazioPrimo
;P. Di Gennaro;
2019
Abstract
The paper investigates the use of poly(1-vinylpyrrolidone-co-2-dimethylaminoethylmetacrilate) (PVP-co-DMAEMA) as a novel coating agent in the preparation of alginate-based microcapsule for the supplement delivery of probiotics. Probiotic Lactobacillus plantarum is used to study the viability of the encapsulated bacterium when exposed to conditions simulating the gastrointestinal tract and industrial process. Results demonstrate that the PVP-co-DMAEMA polymer constitutes a pH-responsive coating suitable for probiotic supplement delivery.
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