A squared coherence (K-2) approach was applied to investigate cerebral autoregulation (CA) in 33 patients (age: 63 14 yrs; 27 males) undergoing surgical aortic valve replacement (SAVR) before surgery (PRE), after surgery (POST) and after a 3-month follow-up (POST3). K-2 was assessed between mean arterial pressure and mean cerebral blood flow velocity in very low frequency (VLF, 0.02-0.07 Hz), low frequency (LF, 0.07-0.15 Hz) and high frequency (HF, 0.15-0.4 Hz) bands at rest in supine position (REST) and during active standing (STAND). The significance of K2 was tested individually via a surrogate approach. Results showed that K2 in HF band increased during POST compared to PRE at REST but this rise was more limited during STAND. Analysis of K2 suggests a possible impairment of CA after SAVR that might expose patients to a higher risk of developing post-surgery cerebrovascular adverse events.

Squared coherence analysis might suggest cerebral autoregulation post-surgery impairment in patients undergoing surgical aortic valve replacement / V. Bari, F. Gelpi, B. Cairo, N. Cornara, B. De Maria, M. Ranucci, A. Porta - In: 2022 12th Conference of the European Study Group on Cardiovascular Oscillations (ESGCO)[s.l] : IEEE Press, 2022. - ISBN 978-1-6654-8513-5. - pp. 1-2 (( Intervento presentato al 12. convegno Conference of the European Study Group on Cardiovascular Oscillations (ESGCO) tenutosi a Štrbské Pleso nel 2022 [10.1109/ESGCO55423.2022.9931376].

Squared coherence analysis might suggest cerebral autoregulation post-surgery impairment in patients undergoing surgical aortic valve replacement

V. Bari
Primo
;
F. Gelpi
Secondo
;
B. Cairo;A. Porta
Ultimo
2022

Abstract

A squared coherence (K-2) approach was applied to investigate cerebral autoregulation (CA) in 33 patients (age: 63 14 yrs; 27 males) undergoing surgical aortic valve replacement (SAVR) before surgery (PRE), after surgery (POST) and after a 3-month follow-up (POST3). K-2 was assessed between mean arterial pressure and mean cerebral blood flow velocity in very low frequency (VLF, 0.02-0.07 Hz), low frequency (LF, 0.07-0.15 Hz) and high frequency (HF, 0.15-0.4 Hz) bands at rest in supine position (REST) and during active standing (STAND). The significance of K2 was tested individually via a surrogate approach. Results showed that K2 in HF band increased during POST compared to PRE at REST but this rise was more limited during STAND. Analysis of K2 suggests a possible impairment of CA after SAVR that might expose patients to a higher risk of developing post-surgery cerebrovascular adverse events.
Settore ING-INF/06 - Bioingegneria Elettronica e Informatica
2022
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2434/954541
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