Despite the COVID-19 pandemic, influenza remains an important issue. Especially in community settings, influenza outbreaks can be difficult to control and can result in high attack rates. In April 2022, a large A(H3N2) influenza outbreak spread in the largest Italian drug-rehabilitation community. One hundred eighty-four individuals presented influenza-like symptoms (attack rate of 26.2%); 56% previously received the influenza vaccine. Sequence analyses highlighted a genetic drift from the vaccine strain, which may have caused the observed lack of protection.

A large A(H3N2) influenza outbreak with a high attack rate in a drug user community in Italy, April 2022 / M. Gori, C. Fappani, S. Bianchi, M. Canuti, D. Colzani, P. Ottogalli, S. Duehren, E. Tanzi, A. Amendola, A. Boschini. - In: EPIDEMIOLOGY AND INFECTION. - ISSN 0950-2688. - (2023). [Epub ahead of print] [10.1017/S0950268823000055]

A large A(H3N2) influenza outbreak with a high attack rate in a drug user community in Italy, April 2022

M. Gori
Primo
;
C. Fappani
Secondo
;
S. Bianchi;M. Canuti;D. Colzani;E. Tanzi;A. Amendola
Penultimo
;
2023

Abstract

Despite the COVID-19 pandemic, influenza remains an important issue. Especially in community settings, influenza outbreaks can be difficult to control and can result in high attack rates. In April 2022, a large A(H3N2) influenza outbreak spread in the largest Italian drug-rehabilitation community. One hundred eighty-four individuals presented influenza-like symptoms (attack rate of 26.2%); 56% previously received the influenza vaccine. Sequence analyses highlighted a genetic drift from the vaccine strain, which may have caused the observed lack of protection.
Settore MED/42 - Igiene Generale e Applicata
Settore MED/07 - Microbiologia e Microbiologia Clinica
2023
19-gen-2023
Article (author)
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2434/951479
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