Ceftriaxone, a third-generation cephalosporin, is commonly used in pediatric patients and is generally well tolerated. Its more frequent adverse effects are biliary pseudolithiasis, urolithiasis, and hemolytic anemia. On the other hand, ceftriaxone-induced acute cholestatic hepatitis is a very rare condition, especially in children. Here, we describe a case of this condition in a young male child to highlight the importance of suspecting this drug-induced liver injury to achieve a prompt diagnosis.

Ceftriaxone-induced cholestatic hepatitis in a child: A case report and a review of the literature / M.L. Castellazzi, C.V. Agostoni, J. Palella, D. Civeriati, P. Marchisio, G. Nebbia. - In: FRONTIERS IN PEDIATRICS. - ISSN 2296-2360. - 10:(2022 Dec), pp. 1051887.1-1051887.6. [10.3389/fped.2022.1051887]

Ceftriaxone-induced cholestatic hepatitis in a child: A case report and a review of the literature

C.V. Agostoni
Secondo
;
J. Palella;D. Civeriati;P. Marchisio
Penultimo
;
2022

Abstract

Ceftriaxone, a third-generation cephalosporin, is commonly used in pediatric patients and is generally well tolerated. Its more frequent adverse effects are biliary pseudolithiasis, urolithiasis, and hemolytic anemia. On the other hand, ceftriaxone-induced acute cholestatic hepatitis is a very rare condition, especially in children. Here, we describe a case of this condition in a young male child to highlight the importance of suspecting this drug-induced liver injury to achieve a prompt diagnosis.
antibiotic; ceftriaxone; children; cholestasis; hepatitis
Settore MED/38 - Pediatria Generale e Specialistica
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2434/950248
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