Clinical potential of Extracellular Vesicles in Regenerative and Aesthetic Medicine

Extracellular vesicles (EVs) represent a heterogeneous class of spherical particles released by cells that are known for the essential role they play in cell to cell communication in various processes, both physiological and pathological. Over the years, they have been considered an useful tool for the diagnosis and treatment of various diseases, mainly cancer. Lately, however, their use has also extended to other fields of medicine, since they could be administered through minimally or non-invasive approaches in clinical treatments. Among those novel application fields, we find the aesthetic medicine, where the use of EVs aims to support skin rejuvenation and to improve and correct skin-related cosmetic defects, including wrinkles, hair loss, and acne scars. This review provides a general perspective and the latest findings supporting the efficacy of EVs application in Aesthetic Medicine.