Intra-operative contrast-enhanced ultrasound (CEUS) is a relatively standardized procedure in brain neurosurgery, but it is still underused in spinal cord and intramedullary tumor evaluation. We reviewed and analyzed the intra-operative data from a surgical series of patients harboring intramedullary spinal cord tumors who underwent surgery under CEUS guidance. CEUS was performed in 12 patients (age range: 13-55 y); all lesions had ill-defined boundaries or peritumoral cysts at preliminary intra-operative B-mode ultrasound. CEUS highlighted the tumors in all cases. The contrast agent's spinal distribution revealed different phases (arterial, peak, washout), as observed in the brain, but these appeared to be slower and less intense. In our experience, intra-operative CEUS allows surgeons to assess spinal cord perfusion and highlight intramedullary tumors in real time. As for other imaging modalities, ultrasound contrast agents add valuable information over baseline imaging, and their use should be fostered to better understand microbubble distribution dynamics. (E-mail: francesco.prada@istituto-besta.it) (c) 2020 World Federation for Ultrasound in Medicine & Biology. All rights reserved.

Contrast-Enhanced Ultrasound Assisted Surgery of Intramedullary Spinal Cord Tumors: Analysis of Technical Benefits and Intra-operative Microbubble Distribution Characteristics / I.G. Vetrano, A.G. Gennari, A. Erbetta, F. Acerbi, V. Nazzi, F. Dimeco, F. Prada. - In: ULTRASOUND IN MEDICINE AND BIOLOGY. - ISSN 0301-5629. - 47:3(2021), pp. 398-407. [10.1016/j.ultrasmedbio.2020.10.017]

Contrast-Enhanced Ultrasound Assisted Surgery of Intramedullary Spinal Cord Tumors: Analysis of Technical Benefits and Intra-operative Microbubble Distribution Characteristics

I.G. Vetrano
Primo
;
F. Acerbi;V. Nazzi;F. Dimeco
Penultimo
;
F. Prada
Ultimo
2021

Abstract

Intra-operative contrast-enhanced ultrasound (CEUS) is a relatively standardized procedure in brain neurosurgery, but it is still underused in spinal cord and intramedullary tumor evaluation. We reviewed and analyzed the intra-operative data from a surgical series of patients harboring intramedullary spinal cord tumors who underwent surgery under CEUS guidance. CEUS was performed in 12 patients (age range: 13-55 y); all lesions had ill-defined boundaries or peritumoral cysts at preliminary intra-operative B-mode ultrasound. CEUS highlighted the tumors in all cases. The contrast agent's spinal distribution revealed different phases (arterial, peak, washout), as observed in the brain, but these appeared to be slower and less intense. In our experience, intra-operative CEUS allows surgeons to assess spinal cord perfusion and highlight intramedullary tumors in real time. As for other imaging modalities, ultrasound contrast agents add valuable information over baseline imaging, and their use should be fostered to better understand microbubble distribution dynamics. (E-mail: francesco.prada@istituto-besta.it) (c) 2020 World Federation for Ultrasound in Medicine & Biology. All rights reserved.
Contrast-enhanced ultrasound; Intra-operative ultrasound; Intramedullary tumors; Spinal glioma; Ultrasound contrast agents; Adolescent; Adult; Contrast Media; Female; Humans; Intraoperative Period; Male; Microbubbles; Middle Aged; Retrospective Studies; Spinal Cord Neoplasms; Young Adult; Ultrasonography, Interventional
Settore MED/27 - Neurochirurgia
Settore MED/37 - Neuroradiologia
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2434/945636
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