This study aimed at providing standardized regression-based (SRB) reliable change indices (RCIs) for the Italian Edinburgh Cognitive and Behavioral ALS Screen (ECAS). Thirty-one consecutive ALS patients undergoing the ECAS were followed-up (T1) at 6.5 +/- 1 months (range = 5-8). Ceiling/floor effects, practice effect, and test-retest reliability were assessed. Each ECAS measure was regressed by stepwise-entering as predictors demographics, respective T0 scores, T0 disease duration and ALSFRS-R, retest interval, and progression rate (Delta FS) - i.e., (48 - ALSFRS-R-T0)/disease duration(T0) in months. Ceiling effects were infrequently detected, no practice effect emerged and all ECAS measures were reliable at retest (except for Language and Visuo-spatial subscales). T0 scores predicted all ECAS measures except for the Visuo-spatial subscale. The availability of RCIs for the Italian ECAS will aid ALS-related clinical practice and research within the longitudinal dimension.

Reliable change indices for the Italian Edinburgh Cognitive and Behavioral ALS Screen (ECAS) / E.N. Aiello, F. Solca, S. Torre, L. Carelli, A. Monti, R. Ferrucci, F. Verde, N. Ticozzi, V. Silani, B. Poletti. - In: AMYOTROPHIC LATERAL SCLEROSIS AND FRONTOTEMPORAL DEGENERATION. - ISSN 2167-8421. - (2022), pp. 1-4. [Epub ahead of print] [10.1080/21678421.2022.2134801]

Reliable change indices for the Italian Edinburgh Cognitive and Behavioral ALS Screen (ECAS)

F. Verde;N. Ticozzi;V. Silani
Penultimo
;
2022

Abstract

This study aimed at providing standardized regression-based (SRB) reliable change indices (RCIs) for the Italian Edinburgh Cognitive and Behavioral ALS Screen (ECAS). Thirty-one consecutive ALS patients undergoing the ECAS were followed-up (T1) at 6.5 +/- 1 months (range = 5-8). Ceiling/floor effects, practice effect, and test-retest reliability were assessed. Each ECAS measure was regressed by stepwise-entering as predictors demographics, respective T0 scores, T0 disease duration and ALSFRS-R, retest interval, and progression rate (Delta FS) - i.e., (48 - ALSFRS-R-T0)/disease duration(T0) in months. Ceiling effects were infrequently detected, no practice effect emerged and all ECAS measures were reliable at retest (except for Language and Visuo-spatial subscales). T0 scores predicted all ECAS measures except for the Visuo-spatial subscale. The availability of RCIs for the Italian ECAS will aid ALS-related clinical practice and research within the longitudinal dimension.
Edinburgh Cognitive and Behavioral ALS Screen; Reliable change index; amyotrophic lateral sclerosis; neuropsychology; psychometrics
Settore MED/26 - Neurologia
Settore M-PSI/08 - Psicologia Clinica
26-ott-2022
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2434/945631
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