Passive immunization with mAbs has been employed in COVID-19. We performed a systematic review of the literature assessing the endogenous humoral immune response against SARS-CoV-2 in patients treated with mAbs. Administration of mAbs in seronegative patients led to a reduction in both antibody titres and neutralizing activity against the virus.

Endogenous antibody response to SARS-CoV-2 in patients who received monoclonal antibodies against COVID-19: A systematic review / A. Lombardi, C. Azzarà, G. Renisi, G. Viero, A. Gori, A. Bandera. - In: CLINICAL IMMUNOLOGY COMMUNICATIONS. - ISSN 2772-6134. - 2:(2022 Dec), pp. 106-109. [10.1016/j.clicom.2022.08.003]

Endogenous antibody response to SARS-CoV-2 in patients who received monoclonal antibodies against COVID-19: A systematic review

A. Lombardi
Primo
;
G. Viero;A. Gori;A. Bandera
2022

Abstract

Passive immunization with mAbs has been employed in COVID-19. We performed a systematic review of the literature assessing the endogenous humoral immune response against SARS-CoV-2 in patients treated with mAbs. Administration of mAbs in seronegative patients led to a reduction in both antibody titres and neutralizing activity against the virus.
Monoclonal antibodies; SARS-CoV-2; Endogenous immune response; Neutralization; Spike protein;
Settore MED/17 - Malattie Infettive
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2434/937582
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