Passive immunization with mAbs has been employed in COVID-19. We performed a systematic review of the literature assessing the endogenous humoral immune response against SARS-CoV-2 in patients treated with mAbs. Administration of mAbs in seronegative patients led to a reduction in both antibody titres and neutralizing activity against the virus.
Endogenous antibody response to SARS-CoV-2 in patients who received monoclonal antibodies against COVID-19: A systematic review / A. Lombardi, C. Azzarà, G. Renisi, G. Viero, A. Gori, A. Bandera. - In: CLINICAL IMMUNOLOGY COMMUNICATIONS. - ISSN 2772-6134. - 2:(2022 Dec), pp. 106-109. [10.1016/j.clicom.2022.08.003]
Endogenous antibody response to SARS-CoV-2 in patients who received monoclonal antibodies against COVID-19: A systematic review
A. Lombardi
Primo
;G. Viero;A. Gori;A. Bandera
2022
Abstract
Passive immunization with mAbs has been employed in COVID-19. We performed a systematic review of the literature assessing the endogenous humoral immune response against SARS-CoV-2 in patients treated with mAbs. Administration of mAbs in seronegative patients led to a reduction in both antibody titres and neutralizing activity against the virus.
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