Aim: The objective of this network meta-analysis was to rank different biomaterials used in adjunct to coronally advanced flap (CAF), based on their performance in root-coverage for Miller's Class I and II gingival recessions.Materials and methods: An electronic database search was carried out in PUBMED, CENTRAL, SCOPUS, and EMBASE to identify the eligible articles and compiled into the citation manager to remove the duplicates. The primary outcome was keratinized gingival tissue width (KGW) and percentage of root coverage (%RC). The treatment effect of different biomaterials was estimated using predictive interval plots and ranked based on biomaterials performance, using multidimensional scale ranking.Results: CAF + connective tissue graft (CTG), CAF + platelet concentrate matrix (PCM) and acellular dermal matrix (ADM) ranked at the top positions in performance in improving KGW. The highest ranked materials in improving percentage of root coverage in gingival recession were CAF + collagen matrix (CM) + gingival fibroblasts (GF), CAF + ADM + platelet rich plasma (PRP) and CAF + ADM, as compared to CAF alone.Conclusion: CTG, ADM, platelet concentrates, and CM + GFs, when used in adjunct to CAF, showed improved stability over >= 12 months of follow-up, better percentage of root coverage, and improved keratinized gingival width.

Stability of biomaterials used in adjunct to coronally advanced flap: A systematic review and network meta-analysis / S. Panda, S. Khijmatgar, H. Arbildo-Vega, A.C. Das, M. Kumar, M. Das, L. Mancini, M. Del Fabbro. - In: CLINICAL AND EXPERIMENTAL DENTAL RESEARCH. - ISSN 2057-4347. - 8:1(2022 Feb), pp. 421-438. [10.1002/cre2.461]

Stability of biomaterials used in adjunct to coronally advanced flap: A systematic review and network meta-analysis

S. Panda
Primo
;
S. Khijmatgar
Secondo
;
M. Del Fabbro
Ultimo
2022

Abstract

Aim: The objective of this network meta-analysis was to rank different biomaterials used in adjunct to coronally advanced flap (CAF), based on their performance in root-coverage for Miller's Class I and II gingival recessions.Materials and methods: An electronic database search was carried out in PUBMED, CENTRAL, SCOPUS, and EMBASE to identify the eligible articles and compiled into the citation manager to remove the duplicates. The primary outcome was keratinized gingival tissue width (KGW) and percentage of root coverage (%RC). The treatment effect of different biomaterials was estimated using predictive interval plots and ranked based on biomaterials performance, using multidimensional scale ranking.Results: CAF + connective tissue graft (CTG), CAF + platelet concentrate matrix (PCM) and acellular dermal matrix (ADM) ranked at the top positions in performance in improving KGW. The highest ranked materials in improving percentage of root coverage in gingival recession were CAF + collagen matrix (CM) + gingival fibroblasts (GF), CAF + ADM + platelet rich plasma (PRP) and CAF + ADM, as compared to CAF alone.Conclusion: CTG, ADM, platelet concentrates, and CM + GFs, when used in adjunct to CAF, showed improved stability over >= 12 months of follow-up, better percentage of root coverage, and improved keratinized gingival width.
CAF; clinical attachment level; keratinised tissue width; network meta-analysis; oral; recession height; recession width; regeneration; root coverage; soft tissue; systematic review; Collagen; Humans; Network Meta-Analysis; Tooth Root; Treatment Outcome; Biocompatible Materials; Gingival Recession
Settore MED/50 - Scienze Tecniche Mediche Applicate
Settore MED/28 - Malattie Odontostomatologiche
feb-2022
29-nov-2021
Article (author)
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2434/935857
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