Objectives: Premature infants are at high risk for hearing loss (HL). The aim of the present study is to assess the frequency of preterm infants affected by HL who experience hearing improvement over months and evaluate possible factors associated with hearing changes. Methods: This retrospective study was conducted in a third-level referral audiologic center. Preterm infants with a confirmed diagnosis of sensorineural HL within the first 3 months of life were reassessed at 18 months corrected age using the click-evoked auditory brainstem response between January 1, 2012, and June 30, 2020. The frequency of hearing improvement and associations between possible risk factors and hearing changes were evaluated. Results: A total of 138 preterm infants (71 male and 67 female; mean gestational age: 30+2 weeks) were assessed. The percentages of hearing improvement and hearing threshold normalization were 58.7% (81/138) and 35.5% (49/138), respectively. We observed a higher frequency of hearing improvement among preterm infants who had received exclusive breastfeeding or mixed feeding compared with those who had received exclusive infant for-mula (80% versus 29.3%, P < 0.001). Conclusion: This study confirms the importance of performing a long audiological follow-up and postponing the indication for cochlear implantation in children with a history of preterm birth. Because of the expression of mesenchymal stem cells and high total antioxidant capacity, breast milk might play a protective role in the auditory system of preterm infants. These findings could have important implications for clinical practice, positively impacting the long-term hearing outcomes of preterm infants.

Hearing outcomes in preterm infants with confirmed hearing loss / M. Alde', F. DI BERARDINO, U. Ambrosetti, S.A.M. Barozzi, G.M.C. Piatti, D. Consonni, D. Zanetti, L. Pignataro, G. Cantarella. - In: INTERNATIONAL JOURNAL OF PEDIATRIC OTORHINOLARYNGOLOGY. - ISSN 0165-5876. - 161:(2022 Oct), pp. 111262.1-111262.6. [10.1016/j.ijporl.2022.111262]

Hearing outcomes in preterm infants with confirmed hearing loss

M. Alde'
Primo
;
F. DI BERARDINO
Secondo
;
U. Ambrosetti;S.A.M. Barozzi;G.M.C. Piatti;D. Zanetti;L. Pignataro
Penultimo
;
G. Cantarella
Ultimo
2022

Abstract

Objectives: Premature infants are at high risk for hearing loss (HL). The aim of the present study is to assess the frequency of preterm infants affected by HL who experience hearing improvement over months and evaluate possible factors associated with hearing changes. Methods: This retrospective study was conducted in a third-level referral audiologic center. Preterm infants with a confirmed diagnosis of sensorineural HL within the first 3 months of life were reassessed at 18 months corrected age using the click-evoked auditory brainstem response between January 1, 2012, and June 30, 2020. The frequency of hearing improvement and associations between possible risk factors and hearing changes were evaluated. Results: A total of 138 preterm infants (71 male and 67 female; mean gestational age: 30+2 weeks) were assessed. The percentages of hearing improvement and hearing threshold normalization were 58.7% (81/138) and 35.5% (49/138), respectively. We observed a higher frequency of hearing improvement among preterm infants who had received exclusive breastfeeding or mixed feeding compared with those who had received exclusive infant for-mula (80% versus 29.3%, P < 0.001). Conclusion: This study confirms the importance of performing a long audiological follow-up and postponing the indication for cochlear implantation in children with a history of preterm birth. Because of the expression of mesenchymal stem cells and high total antioxidant capacity, breast milk might play a protective role in the auditory system of preterm infants. These findings could have important implications for clinical practice, positively impacting the long-term hearing outcomes of preterm infants.
Auditory brainstem responses; Breastfeeding; Hearing improvement; Hearing loss; Preterm infants;
Settore MED/32 - Audiologia
Settore MED/38 - Pediatria Generale e Specialistica
Settore MED/31 - Otorinolaringoiatria
ago-2022
Article (author)
File in questo prodotto:
File Dimensione Formato  
1-s2.0-S0165587622002233-main.pdf

accesso riservato

Tipologia: Publisher's version/PDF
Dimensione 848.61 kB
Formato Adobe PDF
848.61 kB Adobe PDF   Visualizza/Apri   Richiedi una copia
Pubblicazioni consigliate

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2434/935848
Citazioni
  • ???jsp.display-item.citation.pmc??? 0
  • Scopus 1
  • ???jsp.display-item.citation.isi??? 1
social impact