The aim of the present study is to explore the potential association between sleep quality and physical activity (PA) in women carriers of BRCA1/2 mutations. 63 women completed the Pittsburgh Sleep Quality Index (PSQI) and Godin Shepard Leisure-Time Physical Activity Questionnaire (GSL-TPAQ) and were included in the present cross-sectional analysis. Globally, women showed a PSQI score of 7.0 ± 3.6 and a GSL-TPAQ score of 22.8 ± 18.3. Good sleepers (PSQI score ≤ 5) showed signifcantly higher PA levels compared to bad sleepers (PSQI score > 5). Women in the higher tertile of GSL-TPAQ total score (≥ 27 METs/week) have a prevalence ratio (PR) of being a good sleeper of 2.85 (1.25–6.52, 95% confdence intervals) compared to women in the lower tertile (≤11 METs/week). These results were consistent in BRCA1 and BRCA2 women. Considering each single question of PA intensity, the PR of being a good sleeper by unit of increase of MET/week was higher and signifcant in women engaged in strenuous and moderate intensity PA. These results suggests a direct association between PA and sleep quality in women carriers of BRCA mutations.

Physical activity and sleep behaviour in women carrying BRCA1/2 mutations / L. Galasso, L. Castelli, E. Roveda, A. Oliverio, I. Baldassari, F. Esposito, A. Mulè, A. Montaruli, P. Patrizia, E. Bruno. - In: SCIENTIFIC REPORTS. - ISSN 2045-2322. - 12:1(2022), pp. 12873.1-12873.7. [10.1038/s41598-022-16687-1]

Physical activity and sleep behaviour in women carrying BRCA1/2 mutations

L. Galasso
Primo
;
L. Castelli
Secondo
;
E. Roveda;F. Esposito;A. Montaruli;
2022

Abstract

The aim of the present study is to explore the potential association between sleep quality and physical activity (PA) in women carriers of BRCA1/2 mutations. 63 women completed the Pittsburgh Sleep Quality Index (PSQI) and Godin Shepard Leisure-Time Physical Activity Questionnaire (GSL-TPAQ) and were included in the present cross-sectional analysis. Globally, women showed a PSQI score of 7.0 ± 3.6 and a GSL-TPAQ score of 22.8 ± 18.3. Good sleepers (PSQI score ≤ 5) showed signifcantly higher PA levels compared to bad sleepers (PSQI score > 5). Women in the higher tertile of GSL-TPAQ total score (≥ 27 METs/week) have a prevalence ratio (PR) of being a good sleeper of 2.85 (1.25–6.52, 95% confdence intervals) compared to women in the lower tertile (≤11 METs/week). These results were consistent in BRCA1 and BRCA2 women. Considering each single question of PA intensity, the PR of being a good sleeper by unit of increase of MET/week was higher and signifcant in women engaged in strenuous and moderate intensity PA. These results suggests a direct association between PA and sleep quality in women carriers of BRCA mutations.
brca mutation; women; physical activity; sleep
Settore BIO/16 - Anatomia Umana
Settore M-EDF/01 - Metodi e Didattiche delle Attivita' Motorie
Settore M-EDF/02 - Metodi e Didattiche delle Attivita' Sportive
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/2434/935008
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