Use of acridinium-based photocatalyst in the Giese-type coupling of arylboronic acids with electron poor olefins

The development of a visible light-mediated Giese-type reaction using arylboronic acids as aryl radical source is described. The synthetic protocol capitalizes on the employment of environmentally benign metal-free catalyst to forge Csp2-Csp3 bonds. Applications of the methodology to the synthesis of aminoesters and the anti-inflammatory drug nabumetone, either in batch or in flow, are also reported.