Purpose To evaluate the long-term functional and morphological changes occurring in myopic eyes with a dome-shaped macula (DSM), with or without untreated serous retinal detachment (SRD). Methods This prospective, single-centre study enrolled consecutive cases of highly myopic patients with DSM with or without a SRD. Patients underwent complete ophthalmological examinations, optical coherence tomography, axial length measurements and autofluorescence. Follow-up visits were performed with a maximum interval of 6 months for 4 years. Eyes with choroidal neovascularisation were excluded. Results Twenty-six eyes from 18 patients (mean age 61.2) were included. At baseline, 13 eyes had SRD and 13 did not. The DSMs were either horizontal (69%) or round (31%). There were no significant differences in best-corrected visual acuity (BCVA) between eyes with and without SRD during the 48-month follow-up period. Multivariate analysis showed that baseline BCVA was the only parameter among those analysed (age and SRD height) to have a significant effect on the final BCVA (p<0.0001). SRD fluctuated overtime and SRD height was significantly influenced by choroidal thickness (p=0.002). The scleral bulge thickness had no effect on SRD thickness. Conclusions BCVA remained clinically stable over 4 years without treatment despite the fluctuations and persistence of the SRDs.

Long-term natural history of highly myopic eyes with a dome-shaped macula with or without untreated serous retinal detachment : A 4-year follow-up study / F. Viola, G. Leone, E. Garoli, C. Mainetti, D. Galli, A. Invernizzi. - In: BRITISH JOURNAL OF OPHTHALMOLOGY. - ISSN 0007-1161. - 105:10(2021 Oct), pp. 1405-1409. [10.1136/bjophthalmol-2020-316629]

Long-term natural history of highly myopic eyes with a dome-shaped macula with or without untreated serous retinal detachment : A 4-year follow-up study

F. Viola
Primo
;
G. Leone
Secondo
;
E. Garoli;A. Invernizzi
Ultimo
2021-10

Abstract

Purpose To evaluate the long-term functional and morphological changes occurring in myopic eyes with a dome-shaped macula (DSM), with or without untreated serous retinal detachment (SRD). Methods This prospective, single-centre study enrolled consecutive cases of highly myopic patients with DSM with or without a SRD. Patients underwent complete ophthalmological examinations, optical coherence tomography, axial length measurements and autofluorescence. Follow-up visits were performed with a maximum interval of 6 months for 4 years. Eyes with choroidal neovascularisation were excluded. Results Twenty-six eyes from 18 patients (mean age 61.2) were included. At baseline, 13 eyes had SRD and 13 did not. The DSMs were either horizontal (69%) or round (31%). There were no significant differences in best-corrected visual acuity (BCVA) between eyes with and without SRD during the 48-month follow-up period. Multivariate analysis showed that baseline BCVA was the only parameter among those analysed (age and SRD height) to have a significant effect on the final BCVA (p<0.0001). SRD fluctuated overtime and SRD height was significantly influenced by choroidal thickness (p=0.002). The scleral bulge thickness had no effect on SRD thickness. Conclusions BCVA remained clinically stable over 4 years without treatment despite the fluctuations and persistence of the SRDs.
imaging; macula; retina; vision; fluorescein angiography; follow-up studies; humans; middle aged; prospective studies; retrospective studies; tomography, optical coherence; visual acuity; macula lutea; myopia; retinal detachment
Settore MED/30 - Malattie Apparato Visivo
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/2434/929787
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