Quail egg homogenate with zinc as adjunctive therapy in seasonal allergic rhinitis: A randomized controlled trial

Objective. Since most available treatments manage seasonal allergic rhinitis (SAR) show some side effects without reducing recurrences, natural anti-allergic products could represent an interesting treatment addition. We aimed to study the efficacy and tolerance of quail egg as adjunctive therapy in SAR. Methods. In a CONSORT compliant framework, patients with SAR were prospectively randomized to receive mometasone nasal spray for four weeks (M) or the same topic corticosteroid therapy plus oral commercially available quail egg and zinc tablets (M+N). Results. Forty patients were enrolled. The M+N group showed a greater reduction in nasal itching, sneezing, and total nasal symptom scores than the M group. A higher proportion of participants in the M+N group had good rhinitis control than in the M group, with no need for rescue medications. Conclusion. Despite the need for further larger study, quail egg preliminary appears as an effective adjunct to topical steroid therapy in SAR.