We report the case of a patient who developed myoclonus and hyperalgesia following administration of high-dose subarachnoid morphine. This complication occurred with 40-80 mg/day continuous infusion. The pathophysiology of these side effects is discussed.
Hyperalgesia and myoclonus with intrathecal infusion of high-dose morphine / F. De Conno, A. Caraceni, C. Martini, E. Spoldi, M. Salvetti, V. Ventafridda. - In: PAIN. - ISSN 0304-3959. - 47:3(1991), pp. 337-339. [10.1016/0304-3959(91)90225-M]
Hyperalgesia and myoclonus with intrathecal infusion of high-dose morphine
A. Caraceni;
1991
Abstract
We report the case of a patient who developed myoclonus and hyperalgesia following administration of high-dose subarachnoid morphine. This complication occurred with 40-80 mg/day continuous infusion. The pathophysiology of these side effects is discussed.
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