Neuropsychiatric disturbances may occur following interleukin-2 (IL2) administration. We studied the effects of IL2 infusion on cerebral functions in 7 patients with neuropsychological tests and event-related evoked potentials (P300). We observed a failure in the cognitive performances, an increase in latency, and a decrease in amplitude of P300. These effects followed IL2 administration and were reversible.
Neuropsychological and neurophysiological assessment of the central effects of interleukin-2 administration / A. Caraceni, C. Martini, F. Belli, L. Mascheroni, L. Rivoltini, F. Arienti, N. Cascinelli. - In: EUROPEAN JOURNAL OF CANCER. - ISSN 0959-8049. - 29A:9(1993), pp. 1266-1269. [10.1016/0959-8049(93)90070-V]
Neuropsychological and neurophysiological assessment of the central effects of interleukin-2 administration
A. Caraceni;
1993
Abstract
Neuropsychiatric disturbances may occur following interleukin-2 (IL2) administration. We studied the effects of IL2 infusion on cerebral functions in 7 patients with neuropsychological tests and event-related evoked potentials (P300). We observed a failure in the cognitive performances, an increase in latency, and a decrease in amplitude of P300. These effects followed IL2 administration and were reversible.
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