The diterpenoid fraction occurring in the acetone extract of the aerial parts of Scutellaria parvula has been investigated. Only one neoclerodane diterpenoid, scuteparvin, was isolated and its structure elucidated as 4α,18-epoxy-6α-trans-cinnamoyloxy-neoclerod-13-en-15,16-olide, a new natural product. Scuteparvin is quite similar to the already known ajugarin V from Ajuga remota, the only difference being the occurrence of a trans-cinnamoyl ester system instead of an acetate on the 6α-OH group. This finding confirms that the genera Scutellaria and Ajuga are closely related taxonomically.
Scuteparvin, a new neoclerodane diterpenoid from Scutellaria parvula / Maurizio Bruno, Sergio Rosselli, Antonella Maggio, Franco Piozzi, Leonardo Scaglioni, Orietta Servettaz. - In: BIOCHEMICAL SYSTEMATICS AND ECOLOGY. - ISSN 0305-1978. - 32:8(2004 Aug), pp. 755-759.
Scuteparvin, a new neoclerodane diterpenoid from Scutellaria parvula.
Leonardo Scaglioni;
2004
Abstract
The diterpenoid fraction occurring in the acetone extract of the aerial parts of Scutellaria parvula has been investigated. Only one neoclerodane diterpenoid, scuteparvin, was isolated and its structure elucidated as 4α,18-epoxy-6α-trans-cinnamoyloxy-neoclerod-13-en-15,16-olide, a new natural product. Scuteparvin is quite similar to the already known ajugarin V from Ajuga remota, the only difference being the occurrence of a trans-cinnamoyl ester system instead of an acetate on the 6α-OH group. This finding confirms that the genera Scutellaria and Ajuga are closely related taxonomically.
Pubblicazioni consigliate
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
