This review summarizes the latest developments in asymmetric domino reactions, with the emphasis on the preparation of spiro compounds. Discussions on the stereoselectivity of the transformations, the reaction mechanisms, the rationalization of the stereochemical outcome, and the applications of domino reactions to the synthesis of biologically active molecules and natural products are included when appropriate.
Stereoselective domino reactions in the synthesis of spiro compounds / R. Westphal, E. Venturini Filho, F. Medici, M. Benaglia, S. Greco. - In: SYNTHESIS. - ISSN 0039-7881. - 54:13(2022 Jul 01), pp. 2927-2975. [10.1055/a-1771-0641]
Stereoselective domino reactions in the synthesis of spiro compounds
F. Medici;M. Benaglia
;
2022
Abstract
This review summarizes the latest developments in asymmetric domino reactions, with the emphasis on the preparation of spiro compounds. Discussions on the stereoselectivity of the transformations, the reaction mechanisms, the rationalization of the stereochemical outcome, and the applications of domino reactions to the synthesis of biologically active molecules and natural products are included when appropriate.
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a-1771-0641.pdf
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