After 18 months of the COVID-19 pandemic, data concerning SARS-CoV-2 infection in pregnant women and their neonates are progressively taking the place of complete uncertainty. Here, we summarize updated evidence regarding several critical aspects of perinatal SARS-CoV-2 infection, including 1) vertical transmission of the virus in utero, which is possible but seems rare according to current epidemiological data; 2) how COVID-19 during pregnancy can shape maternal and neonatal outcomes, either directly or indirectly; 3) how recommendations regarding the management of infected dyads have been progressively modified in light of new scientific evidence; and 4) how maternal infection or vaccination can induce the passive protection of fetuses and neonates against the infection, through the transfer of specific antibodies before and after birth.
SARS-CoV-2 infection and neonates: Evidence-based data after 18 months of the pandemic / C. Pietrasanta, G. Artieri, A. Ronchi, B. Crippa, C. Ballerini, R. Crimi, F. Mosca, L. Pugni. - In: PEDIATRIC ALLERGY AND IMMUNOLOGY. - ISSN 0905-6157. - 33:S27(2022 Jan), pp. 96-98. [10.1111/pai.13643]
SARS-CoV-2 infection and neonates: Evidence-based data after 18 months of the pandemic
C. Pietrasanta
Primo
;G. Artieri;A. Ronchi;B. Crippa;C. Ballerini;R. Crimi;F. Mosca;L. PugniUltimo
2022
Abstract
After 18 months of the COVID-19 pandemic, data concerning SARS-CoV-2 infection in pregnant women and their neonates are progressively taking the place of complete uncertainty. Here, we summarize updated evidence regarding several critical aspects of perinatal SARS-CoV-2 infection, including 1) vertical transmission of the virus in utero, which is possible but seems rare according to current epidemiological data; 2) how COVID-19 during pregnancy can shape maternal and neonatal outcomes, either directly or indirectly; 3) how recommendations regarding the management of infected dyads have been progressively modified in light of new scientific evidence; and 4) how maternal infection or vaccination can induce the passive protection of fetuses and neonates against the infection, through the transfer of specific antibodies before and after birth.File | Dimensione | Formato | |
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