In this work we applied the direct Directed Transfer Function (dDTF) to fMRI simultaneously recorded with EEG. The objective of the current study is to explore the functional brain network formed by the regions involved in blood oxygen level dependent (BOLD) response related to interictal spikes in temporal lobe epilepsy (TLE). Since fMRI response have been often observed in extratemporal regions, we used a dDTF analysis to study the directionality of the interactions. We demonstrated that this data-driven method of effective connectivity is able to uncovering the information flow between the brain areas involved in the generation of spikes in TLE. ©2009 IEEE.
Exploring brain networks in temporal lobe epilepsy by using dDTF analysis of fMRI data / M.G. Tana, T. Franchin, S. Cerutti, A.M. Bianchi, P. Vitali, F. Villani (INTERNATIONAL IEEE/EMBS CONFERENCE ON NEURAL ENGINEERING). - In: 2009 4th International IEEE/EMBS Conference on Neural Engineering (NER)[s.l] : IEEE, 2009. - ISBN 978-1-4244-2072-8. - pp. 550-553 (( convegno 2009 4th International IEEE/EMBS Conference on Neural Engineering, NER '09 tenutosi a Antalya, tur nel 2009 [10.1109/NER.2009.5109355].
Exploring brain networks in temporal lobe epilepsy by using dDTF analysis of fMRI data
P. Vitali;
2009
Abstract
In this work we applied the direct Directed Transfer Function (dDTF) to fMRI simultaneously recorded with EEG. The objective of the current study is to explore the functional brain network formed by the regions involved in blood oxygen level dependent (BOLD) response related to interictal spikes in temporal lobe epilepsy (TLE). Since fMRI response have been often observed in extratemporal regions, we used a dDTF analysis to study the directionality of the interactions. We demonstrated that this data-driven method of effective connectivity is able to uncovering the information flow between the brain areas involved in the generation of spikes in TLE. ©2009 IEEE.
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