The identification of the full target spectrum of active molecules, known as target deconvolution, has become an indispensable step during the drug discovery process. It is now achievable thanks to mass spectrometry–based technologies. Here we discuss these approaches in the context of epigenetic drug discovery.
Epigenetic drug target deconvolution by mass spectrometry–based technologies / R. Noberini, T. Bonaldi. - In: NATURE STRUCTURAL & MOLECULAR BIOLOGY. - ISSN 1545-9993. - 26:10(2019), pp. 854-857. [10.1038/s41594-019-0279-x]
Epigenetic drug target deconvolution by mass spectrometry–based technologies
T. Bonaldi
Ultimo
Writing – Review & Editing
2019
Abstract
The identification of the full target spectrum of active molecules, known as target deconvolution, has become an indispensable step during the drug discovery process. It is now achievable thanks to mass spectrometry–based technologies. Here we discuss these approaches in the context of epigenetic drug discovery.
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