The human teeth and oral cavity harbor various populations of mesenchymal stem cells (MSCs), so called dental-derived stem cells (D-dSCs) with self-renewing and multilineage differentiation capabilities. D-dSCs properties involves a strong paracrine component resulting from the high levels of bioactive molecules they secrete in response to the local microenvironment. Altogether, this viewpoint develops a general picture of current innovative strategies to employ D-dSCs combined with biomaterials and bioactive factors for regenerative medicine purposes, and offers information regarding the available scientific data and possible applications.
Dental-derived stem cells and biowaste biomaterials : What’s next in bone regenerative medicine applications / M.D. Cosola, S. Cantore, M.G. Balzanelli, C.G. Isacco, K.C.D. Nguyen, R. Saini, A. Malcangi, M. Tumedei, M. Ambrosino, A. Mancini, S. Scacco, R. Nocini, L. Santacroce, A. Ballini, E. Brauner. - In: BIOCELL. - ISSN 0327-9545. - 46:3(2022), pp. 923-929. [10.32604/biocell.2022.018409]
Dental-derived stem cells and biowaste biomaterials : What’s next in bone regenerative medicine applications
M. Tumedei;
2022
Abstract
The human teeth and oral cavity harbor various populations of mesenchymal stem cells (MSCs), so called dental-derived stem cells (D-dSCs) with self-renewing and multilineage differentiation capabilities. D-dSCs properties involves a strong paracrine component resulting from the high levels of bioactive molecules they secrete in response to the local microenvironment. Altogether, this viewpoint develops a general picture of current innovative strategies to employ D-dSCs combined with biomaterials and bioactive factors for regenerative medicine purposes, and offers information regarding the available scientific data and possible applications.File | Dimensione | Formato | |
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