Molecular hydrogen (H2) has been reported to have important biological effects on bone tissue in several in vitro and in vivo models. Danio rerio (zebrafish) embryo is a good model to study osteogenesis because of its transparency, size and rapid development. In zebrafish embryo, hydrogen-rich water (HRW) does not affect vitality or growth rate up to 15%. In addition, 7% HRW treatment enhances zebrafish embryo osteogenesis, increasing the vertebral mineralization rate. In conclusion, we demonstrated the beneficial effects of hydrogen on anabolic bone functions in vivo.

Molecular hydrogen enhances osteogenesis in Danio rerio embryos / M. Carnovali, M. Mariotti, G. Banfi. - In: JOURNAL OF FISH BIOLOGY. - ISSN 0022-1112. - 98:5(2021 May), pp. 1471-1474. [10.1111/jfb.14670]

Molecular hydrogen enhances osteogenesis in Danio rerio embryos

M. Mariotti
Secondo
;
G. Banfi
Ultimo
2021

Abstract

Molecular hydrogen (H2) has been reported to have important biological effects on bone tissue in several in vitro and in vivo models. Danio rerio (zebrafish) embryo is a good model to study osteogenesis because of its transparency, size and rapid development. In zebrafish embryo, hydrogen-rich water (HRW) does not affect vitality or growth rate up to 15%. In addition, 7% HRW treatment enhances zebrafish embryo osteogenesis, increasing the vertebral mineralization rate. In conclusion, we demonstrated the beneficial effects of hydrogen on anabolic bone functions in vivo.
bone; embryo; hydrogen; osteogenesis; zebrafish; animals; calcification, physiologic; embryo, nonmammalian; hydrogen; osteogenesis; zebrafish
Settore MED/04 - Patologia Generale
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2434/893171
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