Fourteen cases of sarcomatoid carcinomas of breast were evaluated by means of a silver technique that selectively stains proteins located in the nucleolar organizer regions (Ag-NORs). The mean area of Ag-NORs (MNORA) was in each case quantitatively analyzed by means of an automated image analyzer. Patients who died early of the disease had a higher MNORA than patients who survived longer than 3 years. The difference was statistically significant. Ag-NORs might be a novel parameter of prognostic relevance in specific cases.
Prognostic relevance of silver-stained nucleolar proteins in sarcomatoid carcinomas of the breast / V. Eusebi, M.G. Cattani, J. Lamovec, D. Trere, C. Ceccarelli, P. Veronesi, C. Clemente, M. Derenzini. - In: ULTRASTRUCTURAL PATHOLOGY. - ISSN 0191-3123. - 15:3(1991 May), pp. 203-214. [10.3109/01913129109021882]
|Titolo:||Prognostic relevance of silver-stained nucleolar proteins in sarcomatoid carcinomas of the breast|
|Parole Chiave:||Breast; Nucleolar organizer regions; Prognosis; Sarcomatoid carcinoma; Adult; Aged; Breast Neoplasms; Carcinoma; Female; Humans; Image Processing, Computer-Assisted; Immunohistochemistry; Middle Aged; Neoplasm Proteins; Nuclear Proteins; Prognosis; Retrospective Studies; Sarcoma; Silver; Staining and Labeling; Survival Rate|
|Settore Scientifico Disciplinare:||Settore MED/18 - Chirurgia Generale|
|Data di pubblicazione:||mag-1991|
|Digital Object Identifier (DOI):||http://dx.doi.org/10.3109/01913129109021882|
|Appare nelle tipologie:||01 - Articolo su periodico|