Glycosphingolipids are amphiphilic plasma membrane components formed by a glycan linked to a specific lipid moiety. In this chapter we report on these compounds, on their role played in our cells to maintain the correct cell biology. In detail, we report on their structure, on their metabolic processes, on their interaction with proteins and from this, their property to modulate positively in health and negatively in disease, the cell signaling and cell biology.
Glycosphingolipids / E. Chiricozzi, M. Aureli, L. Mauri, E. Di Biase, G. Lunghi, M. Fazzari, M. Valsecchi, E.V. Carsana, N. Loberto, A.E.G. Prinetti, A. Sandro Sonnino (ADVANCES IN EXPERIMENTAL MEDICINE AND BIOLOGY). - In: The Role of Glycosylation in Health and Disease / [a cura di] G. Lauc, I. Trbojevic-Akmacic. - Prima edizione. - [s.l] : Springer, 2021. - ISBN 978-3-030-70114-7. - pp. 61-102 [10.1007/978-3-030-70115-4]
Glycosphingolipids
E. Chiricozzi;M. Aureli;L. Mauri;G. Lunghi;M. Fazzari;M. Valsecchi;E.V. Carsana;N. Loberto;A.E.G. Prinetti;
2021
Abstract
Glycosphingolipids are amphiphilic plasma membrane components formed by a glycan linked to a specific lipid moiety. In this chapter we report on these compounds, on their role played in our cells to maintain the correct cell biology. In detail, we report on their structure, on their metabolic processes, on their interaction with proteins and from this, their property to modulate positively in health and negatively in disease, the cell signaling and cell biology.
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