Preoperative anemia creates a challenge for surgical treatment and patient outcomes after major surgery. Prior to a surgical intervention, it is optimal to increase erythropoiesis to improve oxygen transport through the bloodstream for patients at high risk of anemia and to avoid the complications of allogeneic blood transfusion. In this way, patients could receive predeposited autologous blood or, during the surgical procedures, undergo acute normovolemic hemodilution. This approach is allowed by the use of recombinant human erythropoietin in association with erythropoiesis-inducing factors such as iron and folic acid. In this article, we discuss the recent clinical evidences.

Preoperative methods to improve erythropoiesis / A. Bacuzzi, G. Dionigi, G. Piffaretti, M. Tozzi, M.G.L.P.F. Del Romano, F. Villa, S. Cuffari. - In: TRANSPLANTATION PROCEEDINGS. - ISSN 0041-1345. - 43:1(2011 Feb), pp. 324-326. ((Intervento presentato al 9. convegno Luso Brazilian Congress of Transplant : October, 2nd - 5th tenutosi a Porto (Portugal) nel 2010 [10.1016/j.transproceed.2010.09.097].

Preoperative methods to improve erythropoiesis

G. Dionigi
Secondo
;
2011

Abstract

Preoperative anemia creates a challenge for surgical treatment and patient outcomes after major surgery. Prior to a surgical intervention, it is optimal to increase erythropoiesis to improve oxygen transport through the bloodstream for patients at high risk of anemia and to avoid the complications of allogeneic blood transfusion. In this way, patients could receive predeposited autologous blood or, during the surgical procedures, undergo acute normovolemic hemodilution. This approach is allowed by the use of recombinant human erythropoietin in association with erythropoiesis-inducing factors such as iron and folic acid. In this article, we discuss the recent clinical evidences.
Settore MED/18 - Chirurgia Generale
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2434/883008
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