Experimental models of acute pancreatitis have been developed for more than a century. Although not closely comparable to human disease, they have contributed to our understanding of the physiopathology and cell biology of the disease. The methods used for the induction are subjected to critical examination. In the relevant literature findings, the advantages of each group are underscored, and reference is made to their defects with regard to reproducibility and reliability, with a view to extending the results obtained to human pathology. A proper understanding and standardization of these models may enable us to choose the most suitable model for studying a given aspect of the disease or for evaluating new treatment protocols. The data collected has made it possible to select standardization criteria for a comparative experimental study in the laboratory.
Modelli sperimentali di pancreatite acuta. Revisione critica [Experimental models of acute pancreatitis. Critical review] / L. Gaeta, G. Dionigi, R. Dionigi. - In: CHIRURGIA ITALIANA. - ISSN 0009-4773. - 52:5(2000 Oct), pp. 469-497.
|Titolo:||Modelli sperimentali di pancreatite acuta. Revisione critica [Experimental models of acute pancreatitis. Critical review]|
DIONIGI, GIANLORENZO (Secondo)
|Parole Chiave:||experimental acute pancreatitis; experimental models; pancreatitis; acute diseases; models|
|Settore Scientifico Disciplinare:||Settore MED/18 - Chirurgia Generale|
|Data di pubblicazione:||ott-2000|
|Appare nelle tipologie:||01 - Articolo su periodico|