Background: Thyroid hemiagenesis is a rare congenital anomaly, and still more rarely associated with primary hyperparathyroidism (pHPT). Due to the embryologic pathways of the thyroid and parathyroid glands, it remains unclear whether or not thyroid hemiagenesis may be linked to ipsilateral parathyroid agenesis, and consequently, surgical strategy for thyroid hemiagenesis associated pHPT (THAP) does not only depend on preoperative localization but also on the thyroid anomaly. Methods: Including the present case report, a total of nine cases with THAP retrieved from the literature were reviewed. Seven of nine cases had thyroid hemiagenesis on the left side, three out of nine showed a parathyroid adenoma on the contralateral side to the thyroid hemiagenesis. Conclusions: Based on these cases, it can be concluded that the embryologic pathways of the thyroid and parathyroid glands are different, and in cases of THAP, parathyroid exploration should follow standard recommendations for pHPT surgery.

Surgical strategy for primary hyperparathyreoidism with thyroid hemiagenesis / C.C. Ferrari, K. Lorenz, G. Dionigi, H. Dralle. - In: LANGENBECK'S ARCHIVES OF SURGERY. - ISSN 1435-2443. - 399:8(2014), pp. 1077-1081. [10.1007/s00423-014-1228-0]

Surgical strategy for primary hyperparathyreoidism with thyroid hemiagenesis

G. Dionigi;
2014

Abstract

Background: Thyroid hemiagenesis is a rare congenital anomaly, and still more rarely associated with primary hyperparathyroidism (pHPT). Due to the embryologic pathways of the thyroid and parathyroid glands, it remains unclear whether or not thyroid hemiagenesis may be linked to ipsilateral parathyroid agenesis, and consequently, surgical strategy for thyroid hemiagenesis associated pHPT (THAP) does not only depend on preoperative localization but also on the thyroid anomaly. Methods: Including the present case report, a total of nine cases with THAP retrieved from the literature were reviewed. Seven of nine cases had thyroid hemiagenesis on the left side, three out of nine showed a parathyroid adenoma on the contralateral side to the thyroid hemiagenesis. Conclusions: Based on these cases, it can be concluded that the embryologic pathways of the thyroid and parathyroid glands are different, and in cases of THAP, parathyroid exploration should follow standard recommendations for pHPT surgery.
Embryology; Localization; Pediatric surgery; Primary hyperparathyroidism; Thyroid hemiagenesis; Adolescent; Female; Humans; Hyperparathyroidism; Parathyroidectomy; Thyroid Gland; Surgery; Medicine
Settore MED/18 - Chirurgia Generale
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2434/882342
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