Catastrophic antiphospholipid syndrome (CAPS) is a life-threatening condition characterized by multiple thromboembolic events occurring in a short period of time, frequently accompanied by significant systemic inflammation. Aortic involvement is rare in antiphospholipid syndrome and it had been never described in the context of its catastrophic variant. Here, we report an unusual case of aortic occlusion as a debut manifestation of CAPS and discuss its clinical features with an up-to-date review of the literature to identify risk factors and clues for clinical practice.

Catastrophic antiphospholipid syndrome presenting with aortic barrage: case report and review of the literature / L. Moroni, P. Righini, G.A. Ramirez, N. Farina, G. Mancuso, E. Bozzolo, I. Rodriguez-Pinto, R. Cervera, G. Nano, L. Dagna. - In: LUPUS. - ISSN 0961-2033. - 30:6(2021 May 01), pp. 1005-1009. [10.1177/09612033211004728]

Catastrophic antiphospholipid syndrome presenting with aortic barrage: case report and review of the literature

L. Moroni
Primo
;
P. Righini
Secondo
;
N. Farina;G. Nano
Penultimo
;
2021

Abstract

Catastrophic antiphospholipid syndrome (CAPS) is a life-threatening condition characterized by multiple thromboembolic events occurring in a short period of time, frequently accompanied by significant systemic inflammation. Aortic involvement is rare in antiphospholipid syndrome and it had been never described in the context of its catastrophic variant. Here, we report an unusual case of aortic occlusion as a debut manifestation of CAPS and discuss its clinical features with an up-to-date review of the literature to identify risk factors and clues for clinical practice.
Anticardiolipin antibodies; anticoagulation; antiphospholipid syndrome; cardiovascular disease; lupus anticoagulant; thrombosis; Amputation; Antibodies, Antiphospholipid; Antiphospholipid Syndrome; Aortic Diseases; Humans; Lupus Coagulation Inhibitor; Male; Middle Aged; Thrombosis; Iliac Artery
Settore MED/22 - Chirurgia Vascolare
14-apr-2021
Article (author)
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2434/882141
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