Purpose: Intraocular metastasis from a carcinoid tumor is a rare event with anecdotal reports of iris involvement. We describe a case of iris metastasis from a carcinoid tumor treated with photodynamic therapy (PDT). Methods: An isolated iris tumor was observed in a 36-year-old man. Anterior segment photography, fluorescein angiography, and fine-needle aspiration biopsy were performed. The tumor was treated with a bolus application of PDT. Regular follow-up (including clinical and angiographic evaluations) was performed over 2 years. Results: The iris mass was cytologically consistent with metastasis from a mediastinal carcinoid tumor. The metastasis showed prominent vascularization. Bolus PDT was applied with complete and long-term regression of the iris tumor. At the 24-month follow-up, the patient was still alive, and no recurrence had been documented. Conclusions: PDT may be an effective therapeutic option in selected cases of iris metastasis.

Photodynamic therapy for iris metastasis from a mediastinal carcinoid tumor / E. Midena, S. Vujosevic, E. Pilotto. - In: RETINAL CASES & BRIEF REPORTS. - ISSN 1935-1089. - 2:2(2008), pp. 175-177. [10.1097/ICB.0b013e31813c68c8]

Photodynamic therapy for iris metastasis from a mediastinal carcinoid tumor

S. Vujosevic
Secondo
;
2008

Abstract

Purpose: Intraocular metastasis from a carcinoid tumor is a rare event with anecdotal reports of iris involvement. We describe a case of iris metastasis from a carcinoid tumor treated with photodynamic therapy (PDT). Methods: An isolated iris tumor was observed in a 36-year-old man. Anterior segment photography, fluorescein angiography, and fine-needle aspiration biopsy were performed. The tumor was treated with a bolus application of PDT. Regular follow-up (including clinical and angiographic evaluations) was performed over 2 years. Results: The iris mass was cytologically consistent with metastasis from a mediastinal carcinoid tumor. The metastasis showed prominent vascularization. Bolus PDT was applied with complete and long-term regression of the iris tumor. At the 24-month follow-up, the patient was still alive, and no recurrence had been documented. Conclusions: PDT may be an effective therapeutic option in selected cases of iris metastasis.
Settore MED/30 - Malattie Apparato Visivo
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2434/880846
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