We thank Kumar and colleagues for their interest in our new algorithm for risk-stratification in candidates to secondary prophylaxis of variceal bleeding. In this algorithm, patients that bleed without other manifestations of hepatic decompensation are classified as low-risk without measuring the hepatic venous pressure gradient (HVPG). Using our new algorithm, a large number of invasive and costly HVPG measurements can be saved. More importantly, the number of high-risk patients who did not rebleed during follow-up (the "grey zone") decreased from 43% to 23%, demonstrating great accuracy in selecting high-risk patients.
Reply / V. La Mura, C. Villanueva, J.G. Abraldes, J. Bosch. - In: HEPATOLOGY. - ISSN 0270-9139. - 72:4(2020), pp. 1494-1495. [10.1002/hep.31253]
Reply
V. La Mura
Primo
Writing – Original Draft Preparation
;
2020
Abstract
We thank Kumar and colleagues for their interest in our new algorithm for risk-stratification in candidates to secondary prophylaxis of variceal bleeding. In this algorithm, patients that bleed without other manifestations of hepatic decompensation are classified as low-risk without measuring the hepatic venous pressure gradient (HVPG). Using our new algorithm, a large number of invasive and costly HVPG measurements can be saved. More importantly, the number of high-risk patients who did not rebleed during follow-up (the "grey zone") decreased from 43% to 23%, demonstrating great accuracy in selecting high-risk patients.File | Dimensione | Formato | |
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