Several cases of deep venous thrombosis in people who had recently received Vaxzevria (previously known as COVID-19 Vaccine AstraZeneca) have recently been reported, mainly presenting as cerebral vein/cerebral venous sinus thrombosis. This syndrome has been termed “vaccine-induced immune thrombotic thrombocytopenia (VITT)”. Acute spleno-porto-mesenteric vein thrombosis is an uncommon but serious condition with potential sequelae, such as small-bowel gangrene and end-stage liver failure. We describe a case of concomitant thrombosis of portal, superior mesenteric and splenic veins in a young female patient with no other risk factors who received Vaxzevria (previously ChAdOx1 nCoV-19 vaccine, AstraZeneca) 17 days before. The diagnostic workup and the successful endovascular treatment and systemic anticoagulation management is reported.

Successful treatment of acute spleno-porto-mesenteric vein thrombosis after ChAdOx1 nCoV-19 vaccine : a case report / M. Umbrello, N. Brena, R. Vercelli, R.A. Foa, M. Femia, U. Rossi, G.M. Podda, F. Cortellaro, S. Muttini. - In: JOURNAL OF CRITICAL CARE. - ISSN 0883-9441. - 65(2021), pp. 72-75. [10.1016/j.jcrc.2021.05.021]

Successful treatment of acute spleno-porto-mesenteric vein thrombosis after ChAdOx1 nCoV-19 vaccine : a case report

M. Umbrello
;
N. Brena;R. Vercelli;G.M. Podda;
2021

Abstract

Several cases of deep venous thrombosis in people who had recently received Vaxzevria (previously known as COVID-19 Vaccine AstraZeneca) have recently been reported, mainly presenting as cerebral vein/cerebral venous sinus thrombosis. This syndrome has been termed “vaccine-induced immune thrombotic thrombocytopenia (VITT)”. Acute spleno-porto-mesenteric vein thrombosis is an uncommon but serious condition with potential sequelae, such as small-bowel gangrene and end-stage liver failure. We describe a case of concomitant thrombosis of portal, superior mesenteric and splenic veins in a young female patient with no other risk factors who received Vaxzevria (previously ChAdOx1 nCoV-19 vaccine, AstraZeneca) 17 days before. The diagnostic workup and the successful endovascular treatment and systemic anticoagulation management is reported.
COVID-19 vaccine; Splanchnic thrombosis; Thrombocytopenia; Ultrasound-enhanced thrombolysis; VITT; COVID-19 Vaccines; Female; Humans; Mesenteric Veins; SARS-CoV-2; COVID-19; Thrombosis; Vaccines
Settore MED/09 - Medicina Interna
Settore MED/41 - Anestesiologia
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/2434/877002
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