The outcome of lung transplantion (LuTx) suers from a high rejection rate, and there are still huge gapsof knowledge about immune-mediated rejection mechanisms. Acute rejection (AR) can lead to chronic lungallograft dysfunction (CLAD), the main cause of poor survival and low quality of life. The standardized morphologicevaluation of rejection is based on histopathologic diagnostic criteria at a given time-point, but it has a limitedprognostic value towards clinical outcome and the likelihood to develop CLAD. We analyzed immune-check pointproteins in lung tissues of patients who received a LuTx and who were or were not undergoing rejection in theattempt to de

Immune Checkpoint Espression Associates with Rejection in Lung Transplant Recipients / I. Righi, V. Vaira, L. Rosso, L. Morlacchi, M. Cattaneo, S. Ferrero, F. Blasi, M. Nosotti, M. Clerici. ((Intervento presentato al convegno ISHLT 2021 Annual Meeting and Scientific Sessions tenutosi a online nel 2021.

Immune Checkpoint Espression Associates with Rejection in Lung Transplant Recipients

V. Vaira
Secondo
;
L. Rosso;M. Cattaneo;S. Ferrero;F. Blasi;M. Nosotti
Penultimo
;
M. Clerici
Ultimo
2021

Abstract

The outcome of lung transplantion (LuTx) suers from a high rejection rate, and there are still huge gapsof knowledge about immune-mediated rejection mechanisms. Acute rejection (AR) can lead to chronic lungallograft dysfunction (CLAD), the main cause of poor survival and low quality of life. The standardized morphologicevaluation of rejection is based on histopathologic diagnostic criteria at a given time-point, but it has a limitedprognostic value towards clinical outcome and the likelihood to develop CLAD. We analyzed immune-check pointproteins in lung tissues of patients who received a LuTx and who were or were not undergoing rejection in theattempt to de
Settore MED/21 - Chirurgia Toracica
Settore MED/46 - Scienze Tecniche di Medicina di Laboratorio
Settore MED/08 - Anatomia Patologica
Settore MED/10 - Malattie dell'Apparato Respiratorio
Settore MED/04 - Patologia Generale
Immune Checkpoint Espression Associates with Rejection in Lung Transplant Recipients / I. Righi, V. Vaira, L. Rosso, L. Morlacchi, M. Cattaneo, S. Ferrero, F. Blasi, M. Nosotti, M. Clerici. ((Intervento presentato al convegno ISHLT 2021 Annual Meeting and Scientific Sessions tenutosi a online nel 2021.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2434/876724
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