Objectives: Cigarette smoking is related to higher levels of circulating androgens, but its association with androgen receptor (AR) status is still unaddressed. Methods: We analysed, with a case-only approach, smoking habits according to AR status in 112 cases of invasive female breast cancer, from the Piedmont Cancer Registry. We used a multivariate logistic regression model to estimate the odds ratio (OR) and the corresponding confidence interval (CI). Results: The OR of AR-positive breast cancer (versus AR-negative) for ever smokers (versus never) was 2.85 (95% CI 1.02-7.96). Conclusion: Smoking is related to AR-positive breast cancer.

Cigarettes smoking and androgen receptor-positive breast cancer / M. Pizzato, G. Carioli, S. Rosso, R. Zanetti, E. Negri, C. La Vecchia. - In: EUROPEAN JOURNAL OF CANCER PREVENTION. - ISSN 0959-8278. - 30:6(2021 Nov), pp. 469-471. [10.1097/CEJ.0000000000000661]

Cigarettes smoking and androgen receptor-positive breast cancer

M. Pizzato;G. Carioli;E. Negri
;
C. La Vecchia
2021

Abstract

Objectives: Cigarette smoking is related to higher levels of circulating androgens, but its association with androgen receptor (AR) status is still unaddressed. Methods: We analysed, with a case-only approach, smoking habits according to AR status in 112 cases of invasive female breast cancer, from the Piedmont Cancer Registry. We used a multivariate logistic regression model to estimate the odds ratio (OR) and the corresponding confidence interval (CI). Results: The OR of AR-positive breast cancer (versus AR-negative) for ever smokers (versus never) was 2.85 (95% CI 1.02-7.96). Conclusion: Smoking is related to AR-positive breast cancer.
androgen receptor; breast cancer; cigarette smoking
Settore MED/01 - Statistica Medica
23-dic-2020
Article (author)
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2434/871487
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