The ability of bats to coexist with viruses without being harmed is an interesting issue that is still under investigation. Here we use a mathematical model to show that the pattern of body temperature variations observed in bats between day and night is responsible for their ability to keep viruses in check. From the dynamical systems point of view, our model displays an intriguing quasi-periodic behaviour that might be relevant in making the system robust by avoiding viral escape due to perturbations in the body temperature cycle.

Role of body temperature variations in bat immune response to viral infections / M.R. Fumagalli, S. Zapperi, C.A.M. La Porta. - In: JOURNAL OF THE ROYAL SOCIETY INTERFACE. - ISSN 1742-5662. - 18:180(2021 Jul 28). [10.1098/rsif.2021.0211]

Role of body temperature variations in bat immune response to viral infections

M.R. Fumagalli
Primo
;
S. Zapperi
Secondo
;
C.A.M. La Porta
Ultimo
2021-07-28

Abstract

The ability of bats to coexist with viruses without being harmed is an interesting issue that is still under investigation. Here we use a mathematical model to show that the pattern of body temperature variations observed in bats between day and night is responsible for their ability to keep viruses in check. From the dynamical systems point of view, our model displays an intriguing quasi-periodic behaviour that might be relevant in making the system robust by avoiding viral escape due to perturbations in the body temperature cycle.
bats; immunity; interferon-α; virus; Animals; Body Temperature; Immunity; Chiroptera; Virus Diseases; Viruses
Settore MED/04 - Patologia Generale
Settore FIS/03 - Fisica della Materia
Article (author)
File in questo prodotto:
File Dimensione Formato  
Pip_second_revision.pdf

accesso aperto

Tipologia: Post-print, accepted manuscript ecc. (versione accettata dall'editore)
Dimensione 747.37 kB
Formato Adobe PDF
747.37 kB Adobe PDF Visualizza/Apri
Pubblicazioni consigliate

Caricamento pubblicazioni consigliate

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/2434/863226
Citazioni
  • ???jsp.display-item.citation.pmc??? 0
  • Scopus 0
  • ???jsp.display-item.citation.isi??? 0
social impact