Vertically-transmitted bacterial symbionts are widespread in ticks and have manifold impacts on the epidemiology of tick-borne diseases. For instance, they may provide essential nutrients to ticks, affect vector competence, induce immune responses in vertebrate hosts, or even evolve to become vertebrate pathogens. The deer or blacklegged tick Ixodes scapularis harbours the symbiont Rickettsia buchneri in its ovarian tissues. Here we show by molecular, proteomic and imaging methods that R. buchneri is also capable of colonising the salivary glands of wild I. scapularis. This finding has important implications for the diagnosis of rickettsial infections and for pathogen-symbiont interactions in this notorious vector of Lyme borreliosis.

Rickettsia buchneri, symbiont of the deer tick Ixodes scapularis, can colonise the salivary glands of its host / A.M. Al-Khafaji, S.D. Armstrong, I. Varotto Boccazzi, S. Gaiarsa, A. Sinha, Z. Li, D. Sassera, C.K.S. Carlow, S. Epis, B.L. Makepeace. - In: TICKS AND TICK-BORNE DISEASES. - ISSN 1877-959X. - 11:1(2020), pp. 101299.1-101299.6. [10.1016/j.ttbdis.2019.101299]

Rickettsia buchneri, symbiont of the deer tick Ixodes scapularis, can colonise the salivary glands of its host

I. Varotto Boccazzi;S. Gaiarsa;S. Epis;
2020

Abstract

Vertically-transmitted bacterial symbionts are widespread in ticks and have manifold impacts on the epidemiology of tick-borne diseases. For instance, they may provide essential nutrients to ticks, affect vector competence, induce immune responses in vertebrate hosts, or even evolve to become vertebrate pathogens. The deer or blacklegged tick Ixodes scapularis harbours the symbiont Rickettsia buchneri in its ovarian tissues. Here we show by molecular, proteomic and imaging methods that R. buchneri is also capable of colonising the salivary glands of wild I. scapularis. This finding has important implications for the diagnosis of rickettsial infections and for pathogen-symbiont interactions in this notorious vector of Lyme borreliosis.
Biotin synthesis; Midichloria; Rickettsiosis; Symbiosis; Animals; Ixodes; Proteomics; Rickettsia; Salivary Glands; Symbiosis
Settore VET/06 - Parassitologia e Malattie Parassitarie degli Animali
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/2434/862616
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